Date published: 2025-10-10

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Hexaethylene glycol (CAS 2615-15-8)

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Alternate Names:
3,6,9,12,15-Pentaoxaheptadecane-1,17-diol
Application:
Hexaethylene glycol is a surfactant building block
CAS Number:
2615-15-8
Purity:
≥96%
Molecular Weight:
282.33
Molecular Formula:
H(OCH2CH2)6OH
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexaethylene glycol is a surfactant building block and a starting material for macrocyclic polyether preparation. Hexaethylene glycol is a surfactant used as a solvent in paints, lacquers, and varnishes. It is also used as an agent to break down proteins and lipids in biological samples. Hexaethylene glycol also displays antimicrobial activity.


Hexaethylene glycol (CAS 2615-15-8) References

  1. Triple-helix formation by an oligonucleotide containing one (dA)12 and two (dT)12 sequences bridged by two hexaethylene glycol chains.  |  Durand, M., et al. 1992. Biochemistry. 31: 9197-204. PMID: 1390706
  2. Monocomponent hexa- and dodecaethylene glycol succinyl-tocopherol esters: self-assembly structures, cellular uptake and sensitivity to enzyme hydrolysis.  |  Folmer, BM., et al. 2009. Biochem Pharmacol. 78: 1464-74. PMID: 19631613
  3. Tailor-made hexaethylene glycolic ionic liquids as organic catalysts for specific chemical reactions.  |  Jadhav, VH., et al. 2011. Org Lett. 13: 2502-5. PMID: 21488659
  4. Circular dichroism studies of an oligodeoxyribonucleotide containing a hairpin loop made of a hexaethylene glycol chain: conformation and stability.  |  Durand, M., et al. 1990. Nucleic Acids Res. 18: 6353-9. PMID: 2243780
  5. Synthesis of a cholesteryl-HEG phosphoramidite derivative and its application to lipid-conjugates of the anti-HIV 5'TGGGAG³' Hotoda's sequence.  |  Musumeci, D. and Montesarchio, D. 2012. Molecules. 17: 12378-92. PMID: 23090019
  6. DNA nanostructure serum stability: greater than the sum of its parts.  |  Conway, JW., et al. 2013. Chem Commun (Camb). 49: 1172-4. PMID: 23287884
  7. An adaptive biointerface from self-assembled functional peptides for tissue engineering.  |  Li, LL., et al. 2015. Adv Mater. 27: 3181-8. PMID: 25874994
  8. High-resolution electrospray mass spectra of hexaethylene glycol connected biotinylated HNK-1 antigenic trisaccharide molecular probe and its non-sulfated analogue.  |  Chizhov, AO., et al. 2015. Carbohydr Res. 417: 15-8. PMID: 26382082
  9. Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.  |  Klaus, M., et al. 2016. Nucleic Acids Res. 44: 3922-35. PMID: 26939885
  10. 19 F NMR Spectroscopic Analysis of the Binding Modes in Triple-Helical Peptide Nucleic Acid (PNA)/MicroRNA Complexes.  |  Tähtinen, V., et al. 2017. Chemistry. 23: 7113-7124. PMID: 28370485
  11. DNA-Hybridization Detection on Si(100) Surfaces Using Light-Activated Electrochemistry: A Comparative Study between Bovine Serum Albumin and Hexaethylene Glycol as Antifouling Layers.  |  Zarei, L., et al. 2018. Langmuir. 34: 14817-14824. PMID: 30185042
  12. An Improved PEG-Linked Solid Support for Minimizing Process-Related Impurities During Solid-Phase Synthesis of DNA and RNA Sequences.  |  Grajkowski, A., et al. 2021. Curr Protoc. 1: e108. PMID: 33945676
  13. Sequence Preference and Initiator Promiscuity for De Novo DNA Synthesis by Terminal Deoxynucleotidyl Transferase.  |  Schaudy, E., et al. 2021. ACS Synth Biol. 10: 1750-1760. PMID: 34156829
  14. Zeptoliter DNA Origami Reactor to Reveal Cosolute Effects on Nanoconfined G-Quadruplexes.  |  Pandey, S., et al. 2022. J Phys Chem Lett. 13: 8692-8698. PMID: 36094396

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexaethylene glycol, 5 g

sc-255202
5 g
$77.00

Hexaethylene glycol, 25 g

sc-255202A
25 g
$262.00