Date published: 2026-4-28

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Hexadecyl isothiocyanate (CAS 4426-87-3)

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CAS Number:
4426-87-3
Molecular Weight:
283.52
Molecular Formula:
C17H33NS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexadecyl isothiocyanate is a yellow-greenish oily liquid, characterized by its insolubility in water but solubility in organic solvents like ethanol, chloroform, and ether. Its high reactivity, attributed to the isothiocyanate group, readily engages in nucleophilic addition reactions with biological nucleophiles such as thiols and amines. Hexadecyl isothiocyanate holds vast potential for diverse applications across multiple research domains, including biology and chemistry. One notable application lies in its use as a fluorescent probe for visualizing biological molecules and cells. Additionally, it serves as an as a cross-linking agent for protein-protein interactions.


Hexadecyl isothiocyanate (CAS 4426-87-3) References

  1. Synthesis and properties of new thiourea-functionalized poly(propylene imine) dendrimers and their role as hosts for urea functionalized guests.  |  Boas, U., et al. 2001. J Org Chem. 66: 2136-45. PMID: 11300912
  2. RCAI-84, 91, and 105-108, ureido and thioureido analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines.  |  Tashiro, T., et al. 2012. Bioorg Med Chem. 20: 4540-8. PMID: 22739091
  3. The adjuvant activity of aliphatic nitrogenous bases.  |  Gall, D. 1966. Immunology. 11: 369-86. PMID: 5924622

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexadecyl isothiocyanate, 1 g

sc-286012
1 g
$57.00