Date published: 2026-5-2

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Hexacosanoic Acid (CAS 506-46-7)

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Alternate Names:
Ceric acid; Ceratinic acid; Cerotic acid
CAS Number:
506-46-7
Purity:
≥95%
Molecular Weight:
396.68
Molecular Formula:
C26H52O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexacosanoic acid is a long-chain saturated fatty acid that is subject to research in various scientific disciplines. In biochemistry, hexacosanoic acid is studied for its role in the structure and function of cell membranes, as its long hydrocarbon chain influences membrane fluidity and permeability. Furthermore, this compound is utilized in lipidomics to understand the composition and diversity of lipid species in biological systems. In the field of materials science, hexacosanoic acid is of interest for the development of lipid-based coatings and its potential use in the production of bio-lubricants and phase change materials. Environmental scientists investigate hexacosanoic acid in the context of biodegradation processes to evaluate its persistence and breakdown in natural settings.


Hexacosanoic Acid (CAS 506-46-7) References

  1. Correlations of elevated levels of hexacosanoate in erythrocyte membranes with risk factors for atherosclerosis.  |  Antoku, Y., et al. 2000. Atherosclerosis. 153: 169-73. PMID: 11058712
  2. Free radical release in C6 glial cells enriched in hexacosanoic acid: implication for X-linked adrenoleukodystrophy pathogenesis.  |  Di Biase, A., et al. 2004. Neurochem Int. 44: 215-21. PMID: 14602084
  3. Hexacosanoic and docosanoic acids plasma levels in patients with cerebral childhood and asymptomatic X-linked adrenoleukodystrophy: Lorenzo's oil effect.  |  Deon, M., et al. 2008. Metab Brain Dis. 23: 43-9. PMID: 18026827
  4. High levels of saturated very long-chain fatty acid (hexacosanoic acid; C26:0) in whole blood are associated with metabolic syndrome in Japanese men.  |  Kume, A., et al. 2008. Diabetes Res Clin Pract. 80: 259-64. PMID: 18242759
  5. High hexacosanoic acid levels are associated with coronary artery disease.  |  Miyazaki, T., et al. 2014. Atherosclerosis. 233: 429-433. PMID: 24530774
  6. Fatty acid profiles in demented patients: identification of hexacosanoic acid (C26:0) as a blood lipid biomarker of dementia.  |  Zarrouk, A., et al. 2015. J Alzheimers Dis. 44: 1349-59. PMID: 25428249
  7. Accumulation of 24S-hydroxycholesterol in neuronal SK-N-BE cells treated with hexacosanoic acid (C26:0): argument in favor of 24S-hydroxycholesterol as a potential biomarker of neurolipotoxicity.  |  Zarrouk, A., et al. 2015. Rev Neurol (Paris). 171: 125-9. PMID: 25577946
  8. Chemical Synthesis of a Very Long-Chain Fatty Acid, Hexacosanoic Acid (C26:0), and the Ceramide Containing Hexacosanoic Acid.  |  Yamamoto, Y., et al. 2015. J Nutr Sci Vitaminol (Tokyo). 61: 222-7. PMID: 26226958
  9. Oxidative Imbalance, Nitrative Stress, and Inflammation in C6 Glial Cells Exposed to Hexacosanoic Acid: Protective Effect of N-acetyl-L-cysteine, Trolox, and Rosuvastatin.  |  Marchetti, DP., et al. 2018. Cell Mol Neurobiol. 38: 1505-1516. PMID: 30302628
  10. Effects of palmitic acid (16:0), hexacosanoic acid (26:0), ethephon and methyl jasmonate on the cuticular wax composition, structure and expression of key gene in the fruits of three pear cultivars.  |  Wu, X., et al. 2020. Funct Plant Biol. 47: 156-169. PMID: 31930956
  11. Increased synthesis of hexacosanoic acid (C23:0) by cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN).  |  Tsuji, S., et al. 1981. J Biochem. 90: 1233-6. PMID: 7309718
  12. Effects of exogenous hexacosanoic acid on biochemical myelin composition in weaning and post-weaning rats.  |  Di Biase, A., et al. 1997. Neurochem Res. 22: 327-31. PMID: 9051669
  13. Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism.  |  Kobayashi, T., et al. 1997. Biochem Biophys Res Commun. 232: 631-6. PMID: 9126326

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexacosanoic Acid, 50 mg

sc-205340
50 mg
$71.00

Hexacosanoic Acid, 100 mg

sc-205340A
100 mg
$184.00