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Hesperidin (CAS 520-26-3)

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Alternate Names:
Hesperetin 7-rhamnoglucoside; Cirantin; Hesperetin-7- rutinoside
Application:
Hesperidin is a chemopreventive flavonoid
CAS Number:
520-26-3
Purity:
≥95%
Molecular Weight:
610.56
Molecular Formula:
C28H34O15
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hesperidin is a flavonoid that has a broad range of biological activities, such as its anti-inflammatory and antioxidant properties, as well as its role in cellular protection. It has influence on the the metabolic pathways associated with glucose and lipid management. Agricultural research s often examines Hesperidin role in plant defense mechanisms and its impact on the nutritional quality of citrus crops. In environmental studies, the compound is of interest for its potential in bioremediation efforts, where its interactions with other biological systems are considered for maintaining ecological balance.


Hesperidin (CAS 520-26-3) References

  1. Health-promoting effects of the citrus flavanone hesperidin.  |  Li, C. and Schluesener, H. 2017. Crit Rev Food Sci Nutr. 57: 613-631. PMID: 25675136
  2. Potential Anti-inflammatory Effects of Hesperidin from the Genus Citrus.  |  Tejada, S., et al. 2018. Curr Med Chem. 25: 4929-4945. PMID: 28721824
  3. Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence.  |  Hajialyani, M., et al. 2019. Molecules. 24: PMID: 30759833
  4. Hesperidin supplementation has no effect on blood glucose control: A systematic review and meta-analysis of randomized controlled clinical trials.  |  Shams-Rad, S., et al. 2020. Br J Clin Pharmacol. 86: 13-22. PMID: 31489695
  5. Hesperidin: A Therapeutic Agent For Obesity.  |  Xiong, H., et al. 2019. Drug Des Devel Ther. 13: 3855-3866. PMID: 32009777
  6. Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements.  |  Aggarwal, V., et al. 2020. Exp Biol Med (Maywood). 245: 486-497. PMID: 32050794
  7. Effect of Hesperidin on Cardiovascular Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin Bioavailability.  |  Mas-Capdevila, A., et al. 2020. Nutrients. 12: PMID: 32443766
  8. Antioxidant and anti-inflammatory effects of hesperidin methyl chalcone in experimental ulcerative colitis.  |  Guazelli, CFS., et al. 2021. Chem Biol Interact. 333: 109315. PMID: 33171134
  9. Hesperidin: A Review on Extraction Methods, Stability and Biological Activities.  |  Pyrzynska, K. 2022. Nutrients. 14: PMID: 35745117
  10. Hesperidin Functions as an Ergogenic Aid by Increasing Endothelial Function and Decreasing Exercise-Induced Oxidative Stress and Inflammation, Thereby Contributing to Improved Exercise Performance.  |  Imperatrice, M., et al. 2022. Nutrients. 14: PMID: 35889917
  11. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination.  |  Tanaka, T., et al. 1997. Cancer Res. 57: 246-52. PMID: 9000563
  12. Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin.  |  Tanaka, T., et al. 1997. Carcinogenesis. 18: 957-65. PMID: 9163681
  13. Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice.  |  Yang, M., et al. 1997. Int J Cancer. 73: 719-24. PMID: 9398052

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hesperidin, 25 g

sc-205711
25 g
$80.00

Hesperidin, 100 g

sc-205711A
100 g
$200.00

What is the pH of Hesperidin, and how does it compare to Citric Acid?

Asked by: Anonymous
Thank you for your question. We have been unable to find any information on pH. Hesperidin is a phytoestrogen and flavonoid found in citrus plants that exhibits anti-hyperlipidemic, anti-osteoporotic, anti-inflammatory, analgesic, sedative, antinociceptive, and antioxidative activities. Citric acid can function as an iron chelator, support cholesterol/sterol, ubiquinone and isoprenoid biosynthesis in cell culture applications.
Answered by: Technical Support
Date published: 2020-05-21

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. The compound, sc-205711, is provided as a yellow powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-23
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Rated 5 out of 5 by from HongHong, Y. et al. (PubMed 26391026) reported that Hesperidin attenuates learning and memory deficits in APP/PS1 mice through activation of Akt/Nrf2 signaling and inhibition of RAGE/NF- B signaling. -SCBT Publication Review
Date published: 2015-07-02
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Hesperidin is rated 5.0 out of 5 by 1.
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