Molecular structure of Hesperetin 7-O-β-D-Glucuronide, CAS Number: 67322-08-1
Rac Hesperetin 7-O-β-D-Glucuronide (CAS 67322-08-1)
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Alternate Names:
(2S)-3,4-Dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-2H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid
CAS Number:
67322-08-1
Molecular Weight:
478.40
Molecular Formula:
C22H22O12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Hesperetin 7-O-β-D-Glucuronide is a metabolite of Hesperetin, which is the main circulating metabolite involved in osteoblast differentiation. The glucuronidation process is a key phase II metabolic reaction carried out to enhance the solubility of hydrophobic molecules, making them more easily excreted. Hesperetin 7-O-β-D-Glucuronide, as a product of this metabolic pathway From a biochemical perspective, the presence of the glucuronic acid moiety can modulate the interaction of Hesperetin 7-O-β-D-Glucuronide with various enzymes and receptors within the body, altering its kinetic profile. This has implications for understanding the overall impact of flavonoids and their metabolites on health, as well as their mechanism of action at the molecular level.
Rac Hesperetin 7-O-β-D-Glucuronide (CAS 67322-08-1) References
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- Hesperidin metabolite hesperetin-7-O-glucuronide, but not hesperetin-3'-O-glucuronide, exerts hypotensive, vasodilatory, and anti-inflammatory activities. | Yamamoto, M., et al. 2013. Food Funct. 4: 1346-51. PMID: 23831969
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- Mechanism of peroxisome proliferator-activated receptor gamma (PPARγ) transactivation by hesperetin glucuronides is distinct from that by a thiazolidine-2,4-dione agent. | Gamo, K., et al. 2014. Chem Pharm Bull (Tokyo). 62: 491-3. PMID: 24789933
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- Chemical fingerprint and metabolic profile analysis of Citrus reticulate 'Chachi' decoction by HPLC-PDA-IT-MS(n) and HPLC-Quadrupole-Orbitrap-MS method. | Ye, X., et al. 2014. J Chromatogr B Analyt Technol Biomed Life Sci. 970: 108-20. PMID: 25255155
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rac Hesperetin 7-O-β-D-Glucuronide, 5 mg | sc-490393 | 5 mg | $360.00 | |||
Rac Hesperetin 7-O-β-D-Glucuronide, 50 mg | sc-490393A | 50 mg | $2503.00 |