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Heptenophos (CAS 23560-59-0)

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Alternate Names:
Ragadan; XOE 2982; 7-Chlorobicyclo[3.2.0]hepta-2,6-dien-6-yl dimethyl phosphate
CAS Number:
23560-59-0
Molecular Weight:
250
Molecular Formula:
C9H12ClO4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Heptenophos is a chemical compound that functions as an organophosphate insecticide. Its mechanism of action involves inhibiting the activity of acetylcholinesterase, an enzyme responsible for breaking down the neurotransmitter acetylcholine. By doing so, heptenophos disrupts the normal functioning of the nervous system in insects, leading to paralysis and ultimately death. At the molecular level, heptenophos binds to the active site of acetylcholinesterase, preventing it from carrying out its normal function. This results in an accumulation of acetylcholine at the synaptic cleft, leading to continuous stimulation of the postsynaptic neuron and subsequent neurological dysfunction in the insect. In experimental contexts, heptenophos is used to study the effects of acetylcholinesterase inhibition on insect physiology and behavior, providing insights into potential targets for pest control strategies.


Heptenophos (CAS 23560-59-0) References

  1. Assessment of pesticide residues in honey samples from portugal and Spain.  |  Blasco, C., et al. 2003. J Agric Food Chem. 51: 8132-8. PMID: 14690408
  2. Side-effects of three pesticides on the predatory mite, Phytoseiulus persimilis (Acari: Phytoseiidae).  |  Kavousi, A. and Talebi, K. 2003. Exp Appl Acarol. 31: 51-8. PMID: 14756400
  3. Effects of different factors on the residues of heptenophos in cucumber.  |  Talebi, K. and Shaikhi, A. 2003. Commun Agric Appl Biol Sci. 68: 789-93. PMID: 15151314
  4. Efficacy of trimedoxime in mice poisoned with dichlorvos, heptenophos or monocrotophos.  |  Antonijević, B., et al. 2005. Basic Clin Pharmacol Toxicol. 96: 111-7. PMID: 15679473
  5. Sensitive detection of pesticides using amperometric sensors based on cobalt phthalocyanine-modified composite electrodes and immobilized cholinesterases.  |  Skladal, P. and Mascini, M. 1992. Biosens Bioelectron. 7: 335-43. PMID: 1632947
  6. Application of a cholinesterase biosensor to screen for organophosphorus pesticides extracted from soil.  |  Kumaran, S. and Morita, M. 1995. Talanta. 42: 649-55. PMID: 18966276
  7. Multienzyme electrochemical array sensor for determination of phenols and pesticides.  |  Solná, R., et al. 2005. Talanta. 65: 349-57. PMID: 18969806
  8. Compensation for matrix effects in gas chromatography-tandem mass spectrometry using a single point standard addition.  |  Garrido Frenich, A., et al. 2009. J Chromatogr A. 1216: 4798-808. PMID: 19406413
  9. [Antidotal effect of combinations obidoxime/HI-6 and memantine in mice poisoned with soman, dichlorvos or heptenophos].  |  Antonijević, B., et al. 2011. Vojnosanit Pregl. 68: 1033-40. PMID: 22352264
  10. Kinetics of pesticide degradation by human fresh frozen plasma (FFP) in vitro.  |  von der Wellen, J., et al. 2016. Toxicol Lett. 244: 124-128. PMID: 26220518
  11. Lead, cadmium, mercury and insecticide residue control of fresh vegetables.  |  Köck, M., et al. 1989. Geogr Med Suppl. 2: 91-100. PMID: 2744476
  12. Multiresidue Pesticide Analysis in Tea Using GC-MS/MS to Determine 12 Pesticide Residues (GB 2763-2021).  |  Zheng, K., et al. 2022. Molecules. 27: PMID: 36500512
  13. The study of heptenophos and triazophos residues in vegetables treated with the organophosphorus insecticides Hostaquick and Hostathion.  |  Horbowicz, M., et al. 1983. J Environ Sci Health B. 18: 465-72. PMID: 6630896

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Heptenophos, 100 mg

sc-505926
100 mg
$177.00

Heptenophos, 500 mg

sc-505926A
500 mg
$700.00