Molecular structure of Heptachlor epoxide, CAS Number: 1024-57-3
Heptachlor epoxide (CAS 1024-57-3)
Alternate Names:
(1aR,1bS,2R,5S,5aR,6S,6aR)-rel-2,3,4,5,6,7,7-Heptachloro-1a,1b,5,5a,6,6a-hexahydro-2,5-methano-2H-indeno[1,2-b]oxirene; (±)-cis-Heptachlor Epoxide; Epoxyheptachlor
Application:
Heptachlor epoxide is a metabolite of organochlorine pesticide Heptachlor
CAS Number:
1024-57-3
Molecular Weight:
389.32
Molecular Formula:
C10H5Cl7O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Heptachlor epoxide ,aslo know as Epoxyheptachlor, is an organochlorine insecticide that functions by disrupting the insect′s nervous system. It binds to the insect′s nicotinic acetylcholine receptor (nAChR), thereby impeding the function of the neurotransmitter acetylcholine. This interference leads to the paralysis and subsequent death of the insect.
Heptachlor epoxide (CAS 1024-57-3) References
- Down-regulation of particulate protein kinase Cepsilon and up-regulation of nuclear activator protein-1 DNA binding in liver following in vivo exposure of B6C3F1 male mice to heptachlor epoxide. | Hansen, ME. and Matsumura, F. 2001. J Biochem Mol Toxicol. 15: 1-14. PMID: 11170310
- Effects of heptachlor epoxide on components of various signal transduction pathways important in tumor promotion in mouse hepatoma cells. Determination of the most sensitive tumor promoter related effect induced by heptachlor epoxide. | Hansen, ME. and Matsumura, F. 2001. Toxicology. 160: 139-53. PMID: 11246134
- Neurotoxicity of the organochlorine insecticide heptachlor to murine striatal dopaminergic pathways. | Kirby, ML., et al. 2001. Toxicol Sci. 61: 100-6. PMID: 11294980
- Liquid chromatographic separation of the enantiomers of trans-chlordane, cis-chlordane, heptachlor, heptachlor epoxide and alpha-hexachlorocyclohexane with application to small-scale preparative separation. | Champion, WL., et al. 2004. J Chromatogr A. 1024: 55-62. PMID: 14753706
- Carcinogen-metabolizing enzymes and insecticides. | Sheweita, SA. 2004. J Environ Sci Health B. 39: 805-18. PMID: 15620088
- The link between the insecticide heptachlor epoxide, estradiol, and breast cancer. | Cassidy, RA., et al. 2005. Breast Cancer Res Treat. 90: 55-64. PMID: 15770527
- Maternal pregnancy serum level of heptachlor epoxide, hexachlorobenzene, and beta-hexachlorocyclohexane and risk of cryptorchidism in offspring. | Pierik, FH., et al. 2007. Environ Res. 105: 364-9. PMID: 17532317
- Exposure to heptachlor: evaluation of the effects on the larval and adult epidermis of Rana kl. esculenta. | Fenoglio, C., et al. 2009. Aquat Toxicol. 91: 151-60. PMID: 18801586
- Genotoxicity of heptachlor and heptachlor epoxide in human TK6 lymphoblastoid cells. | Prado, G., et al. 2009. Mutat Res. 673: 87-91. PMID: 19146984
- Effects of gestational and lactational exposure to heptachlor epoxide on age at puberty and reproductive function in men and women. | Luderer, U., et al. 2013. Environ Res. 121: 84-94. PMID: 23194642
- Biodegradation of heptachlor and heptachlor epoxide-contaminated soils by white-rot fungal inocula. | Purnomo, AS., et al. 2014. Environ Sci Pollut Res Int. 21: 11305-12. PMID: 24840358
- Association of DDT and heptachlor epoxide in human blood with diabetic nephropathy. | Everett, CJ. and Thompson, OM. 2015. Rev Environ Health. 30: 93-7. PMID: 25822320
- Evaluation of organochlorine pesticide (OCP) residues in meat and edible organs, Iran. | Naseri, K., et al. 2019. Environ Sci Pollut Res Int. 26: 30980-30987. PMID: 31452120
- Enantioselective characteristics, bioaccumulation and toxicological effects of chlordane-related compounds in laying hens. | Liu, X., et al. 2022. Chemosphere. 300: 134486. PMID: 35385762
- Optimization and validation of ultrasound application with a low-temperature method to analyze organochlorine pesticides in smuggled cigarette tobacco. | Domingues, CE., et al. 2022. Anal Methods. 14: 2857-2865. PMID: 35833565
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Heptachlor epoxide, 100 mg | sc-257573 | 100 mg | $312.00 |