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Heparin, Lithium Salt (CAS 9045-22-1)

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Alternate Names:
HEP, Li
Application:
Heparin, Lithium Salt is a mucopolysaccharide that binds to antithrombin III
CAS Number:
9045-22-1
Molecular Weight:
13,500-15,000
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Heparin, Lithium Salt is a complex glycosaminoglycan that has been combined with lithium ions to form a salt. Heparin itself is composed of highly sulfated and variably sized chains of polysaccharide units featuring repeating disaccharide sequences. The lithium salt form of heparin is created by replacing the naturally occurring sodium or other counterions with lithium ions, which may confer distinct properties to the compound in various applications. The structure of heparin is characterized by its high negative charge density due to the presence of sulfate and carboxylate groups, which allow for interaction with positive ions like lithium.


Heparin, Lithium Salt (CAS 9045-22-1) References

  1. Salivary and plasma cortisol response to adrenocorticotropin administration in pigs.  |  Bushong, DM., et al. 2000. Lab Anim. 34: 171-81. PMID: 10817456
  2. Detection of antigen-specific T cells by cytokine flow cytometry: the use of whole blood may underestimate frequencies.  |  Hoffmeister, B., et al. 2003. Eur J Immunol. 33: 3484-92. PMID: 14635059
  3. Influences of enteral nutrition combined with probiotics on gut microflora and barrier function of rats with abdominal infection.  |  Shen, TY., et al. 2006. World J Gastroenterol. 12: 4352-8. PMID: 16865777
  4. Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.  |  Sørensen, H., et al. 2006. Diabetes. 55: 2843-8. PMID: 17003351
  5. A lipophilic statin, pitavastatin, suppresses inflammation-associated mouse colon carcinogenesis.  |  Yasui, Y., et al. 2007. Int J Cancer. 121: 2331-9. PMID: 17657716
  6. The toxicity and pharmacokinetics of dihydrosanguinarine in rat: a pilot study.  |  Vrublova, E., et al. 2008. Food Chem Toxicol. 46: 2546-53. PMID: 18495316
  7. Immune response following vaccination against Salmonella Enteritidis using 2 commercial bacterins in laying hens.  |  Tran, TQ., et al. 2010. Can J Vet Res. 74: 185-92. PMID: 20885842
  8. Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker.  |  Nunes, S., et al. 2013. Cardiovasc Diabetol. 12: 44. PMID: 23497124
  9. Maternal high-salt intake during pregnancy reprogrammed renin-angiotensin system-mediated cardiomyocyte apoptosis in the adult offspring heart.  |  Lv, J., et al. 2014. Reprod Sci. 21: 52-62. PMID: 23690339
  10. Whole blood Nested PCR and Real-time PCR amplification of Talaromyces marneffei specific DNA for diagnosis.  |  Lu, S., et al. 2016. Med Mycol. 54: 162-8. PMID: 26468550
  11. The Timing of Immunomodulation Induced by Mesenchymal Stromal Cells Determines the Outcome of the Graft in Experimental Renal Allotransplantation.  |  Merino, A., et al. 2017. Cell Transplant. 26: 1017-1030. PMID: 28160460
  12. Omega-3 Fish Oil Reduces Mortality Due to Severe Sepsis with Acute Gastrointestinal Injury Grade III.  |  Chen, H., et al. 2017. Pharmacogn Mag. 13: 407-412. PMID: 28839364
  13. HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.  |  Xu, B., et al. 2019. Brain Behav Immun. 76: 223-235. PMID: 30476565
  14. Obestatin ameliorates water retention in chronic heart failure by downregulating renal aquaporin 2 through GPR39, V2R and PPARG signaling.  |  Bao, LZ., et al. 2019. Life Sci. 231: 116493. PMID: 31153818
  15. MIF inhibitor ISO-1 alleviates severe acute pancreatitis-associated acute kidney injury by suppressing the NLRP3 inflammasome signaling pathway.  |  Liu, Y., et al. 2021. Int Immunopharmacol. 96: 107555. PMID: 33823428

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Heparin, Lithium Salt, 100 KU

sc-203997
100 KU
$146.00

Heparin, Lithium Salt, 500 KU

sc-203997A
500 KU
$520.00

Heparin, Lithium Salt, 1000 KU

sc-203997B
1000 KU
$988.00

Thare is no any specification of lithium heparin, I want total specification data of above product.

Asked by: KIRIT
Thank you for your question. Please contact our technical service team directly so we can send you a certificate of analysis.
Answered by: Tech Support Europe
Date published: 2022-08-03

I am interested  to order heparin lithium salt cas #9045-22-1 for our Osmosis Lab. But I just want to confirm how many mg/grams of lithium heparin (100IU) required for 500 ml sheep blood? 

Asked by: Tina Esteban
Thank you for your question. Addition of 70 to 150 units of heparin sodium per 10 to 20 mL sample of whole blood is usually employed to prevent coagulation of the sample. Leukocyte counts should be performed on heparinized blood within two hours after addition of the heparin. We offer Heparin, Lithium Salt (CAS 9045-22-1) in 100, 500, and 1000 kU sizes, with approximately 140 units/mg of the product. For further information please contact technical service.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06
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Rated 5 out of 5 by from GunesGunes, A. et al. (PubMed 26037596) reported that Heparin, a mucopolysaccharide that binds to antithrombin III, increases thioredoxin interacting protein expression in hepatocellular carcinoma cells. -SCBT Publication Review
Date published: 2015-07-06
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Heparin, Lithium Salt is rated 5.0 out of 5 by 1.
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