Heparin disaccharide IV-S, sodium Salt (CAS 136098-08-3)

Heparin disaccharide IV-S, sodium salt, is a derivative of heparin, specifically consisting of a disaccharide unit. It plays a key role in elucidating the biochemical and structural properties of heparin and its interaction with proteins, such as antithrombin and other glycosaminoglycan-binding proteins. This disaccharide unit, which retains the sulfate groups characteristic of heparin′s anticoagulant activity, allows researchers to understand the specific molecular interactions between heparin and its biological targets. In research, this compound is valuable for studying heparin′s structure-activity relationship by isolating the minimal structural unit required for interaction with protein targets. This helps in identifying the binding motifs and essential sulfate patterns necessary for biological activity. The sodium salt form ensures solubility and stability, making it suitable for biochemical assays. Additionally, Heparin disaccharide IV-S, sodium salt, is crucial in examining the fine specificity of heparin-protein interactions, especially in assays involving coagulation factors and other heparin-binding proteins. It aids in exploring the mechanistic roles of sulfation patterns in modulating biological activity and binding affinity. Researchers use this compound to dissect the structure-function relationships that define the anticoagulant and protein-binding properties of heparin, ultimately aiding in understanding heparin′s complex biological activity.