Heparin disaccharide IV-A sodium salt (CAS 136098-07-2)

Heparin disaccharide IV-A sodium salt, a derivative of heparin, has emerged as a crucial tool in glycobiology research due to its structural simplicity and biological significance. This disaccharide unit consists of a glucuronic acid residue linked to an N-acetylglucosamine residue via a 1→4 glycosidic bond, representing a fundamental building block of heparin and heparan sulfate polysaccharides. Researchers have extensively utilized heparin disaccharide IV-A sodium salt as a model system to investigate various aspects of glycosaminoglycan biology, including biosynthesis, structure-function relationships, and molecular recognition. Its interactions with proteins, growth factors, enzymes, and other biomolecules have been explaind using techniques such as nuclear magnetic resonance spectroscopy, X-ray crystallography, surface plasmon resonance, and molecular modeling. Moreover, heparin disaccharide IV-A sodium salt has been employed in studies exploring the roles of heparin/heparan sulfate in cellular signaling, inflammation, angiogenesis, and cancer progression. By dissecting the molecular mechanisms underlying these processes, researchers aim to unravel the complex biological functions of heparin and heparan sulfate in health and disease. Furthermore, heparin disaccharide IV-A sodium salt serves as a valuable tool for developing glycan-based research tools, biomaterials, and diagnostic probes targeting glycosaminoglycan-mediated interactions, paving the way for innovative strategies in drug discovery and regenerative medicine.