Molecular structure of Heparin disaccharide II-S sodium salt, CAS Number: 136098-05-0
Heparin disaccharide II-S sodium salt (CAS 136098-05-0)
Alternate Names:
α-δUA-[1→4]-GlcNS-6S
Application:
Heparin disaccharide II-S sodium salt is a product of heparin and heparin sulphate digestion
CAS Number:
136098-05-0
Molecular Weight:
563.35
Molecular Formula:
C12H16NO16S2•3Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Not available for sale in the US.
Not available for sale in the US.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Heparin disaccharide II-S sodium salt is recognized for its ability to impede the functions of thrombin and factor Xa, enzymes to the coagulation cascade. Its interaction with antithrombin III (ATIII) enhances ATIII′s inhibitory effect on these enzymes. Heparin disaccharide II-S sodium salt associates with heparin cofactor II (HCII), further inhibiting thrombin′s activity. It also serves as a tool in biochemistry for the study of enzymes that interact with heparin and heparan sulfate, such as heparinases and sulfatases. Moreover, this compound′s consistent and well-defined structure makes it useful in research focused on glycomics and the study of glycan patterns and functions.
Heparin disaccharide II-S sodium salt (CAS 136098-05-0) References
- The binding surface and affinity of monomeric and dimeric chemokine macrophage inflammatory protein 1 beta for various glycosaminoglycan disaccharides. | McCornack, MA., et al. 2003. J Biol Chem. 278: 1946-56. PMID: 12411442
- The characterization and molecular structure of hepatoproliferin: a liver regeneration factor from rat hepatocytes. | Oosthuizen, MM. and Lambrechts, H. 2007. Biofactors. 30: 49-65. PMID: 18198401
- Salt-free fractionation of complex isomeric mixtures of glycosaminoglycan oligosaccharides compatible with ESI-MS and microarray analysis. | Liu, H., et al. 2019. Sci Rep. 9: 16566. PMID: 31719635
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Heparin disaccharide II-S sodium salt, 500 µg | sc-215134 | 500 µg | $389.00 | |||
Heparin disaccharide II-S sodium salt, 1 mg | sc-215134A | 1 mg | $633.00 |