Helicobacter pylori Antibody (3-15-45-2): sc-73509

Helicobacter pylori Antibody (3-15-45-2) is a mouse monoclonal IgG1 antibody that specifically detects Helicobacter pylori (H. pylori) by enzyme-linked immunosorbent assay (ELISA). H. pylori monoclonal antibody (3-15-45-2) recognizes this spiral-shaped Gram-negative bacterium that plays a significant role in gastrointestinal diseases, including peptic ulcers and gastritis, affecting approximately 66% of the global population, although many remain asymptomatic. H. pylori (3-15-45-2) antibody targets this bacterium, which is particularly notable for its ability to survive in the harsh acidic environment of the stomach, where H. pylori can be found in various locations such as the mucus layer, attached to epithelial cells, or within vacuoles of epithelial cells. H. pylori′s structure is crucial for its function, as H. pylori possesses specialized adhesins that facilitate binding to membrane-associated lipids and carbohydrates, enhancing its ability to colonize the gastric epithelium. Additionally, H. pylori produces a hydrogenase enzyme that allows H. pylori to utilize molecular hydrogen generated by other intestinal bacteria for energy, while its urease activity converts urea into ammonia and bicarbonate, effectively neutralizing stomach acidity and creating a more hospitable environment for survival. H. pylori monoclonal antibody (3-15-45-2) serves as an essential tool for researchers studying this pathogen and its associated diseases, providing a reliable means to detect and quantify H. pylori in various samples.

The preferred Helicobacter pylori antibody is Helicobacter pylori Antibody (51-13): sc-57778.