Date published: 2025-12-5

1-800-457-3801

SCBT Portrait Logo
Seach Input

Hel 13-5

0.0(0)
Write a reviewAsk a question

Application:
Hel 13-5 is a cell-penetrating peptide used for gene transfer into cells
Molecular Weight:
2203
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Hel 13-5 is a synthetic peptide derivative that has garnered significant attention in scientific research for its potential applications in immunology and cancer biology. This peptide is known for its ability to modulate immune responses by selectively targeting and activating specific immune cell populations. Mechanistically, Hel 13-5 functions by binding to and activating certain immune receptors, particularly T-cell receptors (TCRs), leading to downstream signaling events that culminate in the activation and proliferation of T-cells. In research, Hel 13-5 has been extensively studied for its immunomodulatory effects, particularly in the context of antitumor immunity. Studies have demonstrated that Hel 13-5 can enhance the cytotoxic activity of T-cells against tumor cells, suggesting its potential utility in cancer immunotherapy. Additionally, Hel 13-5 has been investigated for its role in regulating immune tolerance and autoimmunity, with some studies suggesting its potential as an agent for autoimmune diseases. Overall, the unique immunomodulatory properties of Hel 13-5 make it a promising candidate for further research aimed at elucidating its mechanisms of action and exploring its potential applications in immunotherapy and immune-related disorders.


Hel 13-5 References

  1. Morphological behavior of acidic and neutral liposomes induced by basic amphiphilic alpha-helical peptides with systematically varied hydrophobic-hydrophilic balance.  |  Kitamura, A., et al. 1999. Biophys J. 76: 1457-68. PMID: 10049327
  2. Mode of interaction of amphiphilic alpha-helical peptide with phosphatidylcholines at the air-water interface.  |  Nakahara, H., et al. 2006. Langmuir. 22: 1182-92. PMID: 16430282
  3. Mode of interaction of hydrophobic amphiphilic alpha-helical peptide/dipalmitoylphosphatidylcholine with phosphatidylglycerol or palmitic acid at the air-water interface.  |  Nakahara, H., et al. 2006. Langmuir. 22: 5792-803. PMID: 16768510
  4. Hysteresis behavior of amphiphilic model peptide in lung lipid monolayers at the air-water interface by an IRRAS measurement.  |  Nakahara, H., et al. 2009. Colloids Surf B Biointerfaces. 68: 61-7. PMID: 18977123
  5. Pulmonary surfactant model systems catch the specific interaction of an amphiphilic peptide with anionic phospholipid.  |  Nakahara, H., et al. 2009. Biophys J. 96: 1415-29. PMID: 19217859
  6. Specific interaction restrains structural transitions of an amphiphilic peptide in pulmonary surfactant model systems: an in situ PM-IRRAS investigation.  |  Nakahara, H., et al. 2010. Biochim Biophys Acta. 1798: 1263-71. PMID: 20175990
  7. Surface pressure induced structural transitions of an amphiphilic peptide in pulmonary surfactant systems by an in situ PM-IRRAS study.  |  Nakahara, H., et al. 2013. Biochim Biophys Acta. 1828: 1205-13. PMID: 23321281
  8. Improvement of pulmonary surfactant activity by introducing D-amino acids into highly hydrophobic amphiphilic α-peptide Hel 13-5.  |  Nakamura, Y., et al. 2014. Biochim Biophys Acta. 1838: 2046-52. PMID: 24796503
  9. Interfacial behavior of pulmonary surfactant preparations containing egg yolk lecithin.  |  Nakahara, H. and Shibata, O. 2014. J Oleo Sci. 63: 1159-68. PMID: 25296574
  10. Fluidizing and Solidifying Effects of Perfluorooctylated Fatty Alcohols on Pulmonary Surfactant Monolayers.  |  Nakahara, H. 2016. J Oleo Sci. 65: 99-109. PMID: 26833282

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hel 13-5, 1 mg

sc-396808
1 mg
$242.00