Molecular structure of HDS 029, CAS Number: 881001-19-0
HDS 029 (CAS 881001-19-0)
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Alternate Names:
EGFR/ErbB-2/ErbB-4 Inhibitor
Application:
HDS 029 is A potent inhibitor of EGF receptor family
CAS Number:
881001-19-0
Purity:
≥95%
Molecular Weight:
355.76
Molecular Formula:
C17H11ClFN5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
HDS 029 is a potent inhibitor of the ErbB receptor family (IC50 values are 0.3, 0.5 and 1.1 nM for EGFR (ErbB1), ErbB-4 (ErbB4) and Neu (ErbB2) respectively). It inhibits EGF-induced EGFR (erbB1) autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB autophosphorylation in MDA-MB-453 human breast carcinoma cells (IC50 values are 2.5 and 24 nM respectively).
HDS 029 (CAS 881001-19-0) References
- Basal cell signaling by p63 controls luminal progenitor function and lactation via NRG1. | Forster, N., et al. 2014. Dev Cell. 28: 147-60. PMID: 24412575
Inhibitor of:
EGFR, ErbB-4, and Neu.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HDS 029, 1 mg | sc-203995 | 1 mg | $114.00 | |||
| US: Only available in the US | ||||||