hCAP-G Antibody (YY-2): sc-101014
- hCAP-G Antibody (YY-2) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant hCAP-G of human origin
- recommended for detection of hCAP-G of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for hCAP-G Antibody (YY-2). This work is in progress.
hCAP-G Antibody (YY-2) is a mouse monoclonal IgG1 antibody that detects hCAP-G (condensin complex subunit 3) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). hCAP-G is a crucial regulatory subunit of the condensin complex, which plays a vital role in the organization and segregation of chromosomes during cell division. This 1,015 amino acid protein, encoded by the human gene NCAPG, is characterized by ten HEAT repeats, which are essential for structural integrity and function. The condensin complex converts interphase chromatin into mitotic-like condensed chromosomes, a process critical for accurate chromosome segregation. hCAP-G is predominantly located in the cytoplasm during interphase, with a portion associated with chromatin, and translocates to the chromatin during mitosis, where CDC2 phosphorylates hCAP-G at the onset of prophase. This phosphorylation facilitates condensin association with chromosome arms, leading to chromosome condensation. The dynamic localization and modification of hCAP-G underscore genomic stability importance, making anti-hCAP-G antibody (YY-2) an invaluable tool for researchers studying cell division and related processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
hCAP-G Antibody (YY-2) | sc-101014 | 100 µg/ml | $339.00 |