CD44 Antibody (KM114): sc-18882
- CD44 Antibody (KM114) is a rat monoclonal IgG1, cited in 3 publications, provided at 200 µg/ml
- recommended for detection of HCAM of mouse, rat and human origin by WB, IP and FCM
- available conjugated to phycoerythrin for IF, IHC(P) and FCM
- also provided azide-free for blocking the adhesion of a B-cell hybridoma, sc-18882 L, 200 µg/0.1 ml
- See CD44 (DF1485): sc-7297 for CD44 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD44 Antibody (KM114). This work is in progress.
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SEE ALSO...
HCAM Antibody (KM114) is a rat monoclonal IgG1 antibody that detects HCAM in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). HCAM, also known as CD44, is a critical cell adhesion molecule that plays a vital role in various biological processes, including hematopoiesis, lymphocyte activation, and tumor metastasis. This 742 amino acid single-pass type I membrane protein functions primarily as a receptor for hyaluronic acid (HA), facilitating essential cell-cell and cell-matrix interactions that are crucial for cell adhesion and migration. Notably, HCAM undergoes alternative splicing, resulting in multiple isoforms, including CD44R, CDw44, CD44S, CD44H, and CD44E, each with distinct expression patterns and functional implications. CD44H shows elevated expression in cancer tissues, highlighting its significant role in tumor progression and suggesting potential therapeutic applications. With its ability to interact with ligands such as osteopontin, anti-HCAM antibody (KM114) serves as an invaluable tool for researchers investigating the mechanisms of cell adhesion and migration in both normal and pathological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (KM114) | sc-18882 | 200 µg/ml | $322.00 | |||
CD44 Antibody (KM114) L | sc-18882 L | 200 µg/0.1 ml | $322.00 | |||
CD44 Antibody (KM114) PE | sc-18882 PE | 200 µg/ml | $349.00 |