CD44 Antibody (IRAWB 14.4): sc-65876
- CD44 Antibody (IRAWB 14.4) is a rat monoclonal IgG2a, cited in 1 publications, provided at 200 µg/ml
- raised against an HA-binding varient of a T-cell line derived from a spontaneous tumor of mouse origin
- recommended for detection of HCAM of mouse origin by FCMIHC(P)
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD44 (DF1485): sc-7297 for CD44 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD44 Antibody (IRAWB 14.4). This work is in progress.
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SEE ALSO...
HCAM Antibody (IRAWB 14.4) is a rat monoclonal IgG2a antibody that detects HCAM in mouse samples through applications such as flow cytometry (FCM) and immunohistochemistry with paraffin-embedded sections (IHCP). HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, which are vital processes in embryogenesis, immune response, and tumor metastasis. HCAM (IRAWB 14.4) antibody recognizes a protein that functions as a receptor for hyaluronic acid (HA) and interacts with various ligands, including osteopontin (OPN), facilitating both cell-cell and cell-matrix interactions. HCAM expression is particularly significant in cancer, as one isoform, CD44H, appears at elevated levels in tumor tissues, indicating potential involvement in tumor progression and metastasis. HCAM undergoes alternative splicing, resulting in multiple isoforms such as CD44R, CDw44, CD44S, and CD44E, which are differentially expressed across various tissues. HCAM-mediated interactions underscore a significant role in maintaining cellular architecture and influencing cellular behavior in both normal and pathological states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (IRAWB 14.4) | sc-65876 | 200 µg/ml | $322.00 | |||
CD44 Antibody (IRAWB 14.4) FITC | sc-65876 FITC | 200 µg/ml | $336.00 | |||
CD44 Antibody (IRAWB 14.4) PE | sc-65876 PE | 200 µg/ml | $349.00 |