CD44 Antibody (IM7): sc-18849
- CD44 Antibody (IM7) is a rat monoclonal IgG2b, cited in 48 publications, provided at 200 µg/ml
- raised against Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1
- Anti-CD44 Antibody (IM7) is recommended for detection of HCAM of mouse, rat, human, canine, feline and equine origin by WB, IP, IF, IHC(P) and FCM
- Anti-CD44 Antibody (IM7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD44 Antibody (IM7). This work is in progress.
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SEE ALSO...
HCAM Antibody (IM7) is a rat monoclonal IgG2b antibody that detects HCAM in mouse, rat, human, canine, feline, and equine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-HCAM antibody (IM7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, functioning as a receptor for hyaluronic acid (HA) and interacting with ligands such as osteopontin (OPN). This interaction mediates cell-cell and cell-matrix connections, essential during processes like hematopoiesis, lymphocyte activation, and tumor metastasis. HCAM′s structure includes a Link domain and undergoes alternative splicing, resulting in multiple isoforms, including CD44R, CDw44, CD44S, CD44H (hematopoietic), and CD44E (epithelial). CD44H isoform shows high expression in cancer tissues, indicating a significant role in tumor progression and highlighting HCAM′s importance in both normal physiological processes and pathological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (IM7) | sc-18849 | 200 µg/ml | $322.00 | |||
CD44 Antibody (IM7) AC | sc-18849 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD44 Antibody (IM7) HRP | sc-18849 HRP | 200 µg/ml | $322.00 | |||
CD44 Antibody (IM7) FITC | sc-18849 FITC | 200 µg/ml | $336.00 | |||
CD44 Antibody (IM7) PE | sc-18849 PE | 200 µg/ml | $349.00 | |||
CD44 Antibody (IM7) Alexa Fluor® 488 | sc-18849 AF488 | 200 µg/ml | $364.00 | |||
CD44 Antibody (IM7) Alexa Fluor® 546 | sc-18849 AF546 | 200 µg/ml | $364.00 | |||
CD44 Antibody (IM7) Alexa Fluor® 594 | sc-18849 AF594 | 200 µg/ml | $364.00 | |||
CD44 Antibody (IM7) Alexa Fluor® 647 | sc-18849 AF647 | 200 µg/ml | $364.00 | |||
CD44 Antibody (IM7) Alexa Fluor® 680 | sc-18849 AF680 | 200 µg/ml | $364.00 | |||
CD44 Antibody (IM7) Alexa Fluor® 790 | sc-18849 AF790 | 200 µg/ml | $364.00 |