Halofuginone Hydrochloride (CAS 1217623-74-9)
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Halofuginone Hydrobromide is a compound with a broad range of applications in research, particularly in the study of biological pathways and cellular processes. In the field of biochemistry, researchers utilize halofuginone hydrobromide to investigate its inhibitory effects on the enzyme collagen type I synthesis. Additionally, halofuginone hydrobromide is used to explore its role in the inhibition of the Th17 differentiation pathway, which is relevant in immunological studies. This chemical is also a subject of interest in agricultural research, where its impact on the growth and development of parasites is examined. Furthermore, in the context of molecular biology, halofuginone hydrobromide is utilized to gain insights into the mechanisms of amino acid starvation response, as it can mimic the conditions that activate the amino acid deprivation response.
Halofuginone Hydrochloride (CAS 1217623-74-9) References
- Halofuginone inhibits tumor growth in the polyoma middle T antigen mouse via a thrombospondin-1 independent mechanism. | Yee, KO., et al. 2006. Cancer Biol Ther. 5: 218-24. PMID: 16418571
- Phase I and pharmacokinetic study of halofuginone, an oral quinazolinone derivative in patients with advanced solid tumours. | de Jonge, MJ., et al. 2006. Eur J Cancer. 42: 1768-74. PMID: 16815702
- Dihydroxylation of vinyl sulfones: stereoselective synthesis of (+)- and (-)-febrifugine and halofuginone. | McLaughlin, NP. and Evans, P. 2010. J Org Chem. 75: 518-21. PMID: 20000346
- Development and comparison of HPLC-MS/MS and UPLC-MS/MS methods for determining eight coccidiostats in beef. | Zhao, X., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1087-1088: 98-107. PMID: 29730532
- Synthesis and in vitro antileishmanial efficacy of novel quinazolinone derivatives. | Prinsloo, IF., et al. 2021. Chem Biol Drug Des. 97: 383-398. PMID: 32914553
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Halofuginone Hydrochloride, 0.5 mg | sc-211579 | 0.5 mg | $461.00 |