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H-Leu-Leu-OMe Hydrochloride (CAS 6491-83-4)

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Application:
H-Leu-Leu-OMe Hydrochloride is an immunosuppressant for biological applications
CAS Number:
6491-83-4
Purity:
≥95%
Molecular Weight:
294.82
Molecular Formula:
C13H26N2O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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H-Leu-Leu-OMe Hydrochloride is a dipeptide methyl ester. By interacting with proteases, it can be used to investigate the specificity, mechanism, and kinetics of protease action. This information is used for understanding the role of proteases in physiological processes as well as for designing inhibitors. The methyl ester group in H-Leu-Leu-OMe Hydrochloride makes it more resistant to hydrolysis by certain peptidases compared to its non-esterified counterparts, allowing for more detailed studies on enzyme selectivity and function. The incorporation of the hydrochloride salt enhances the compound′s solubility in aqueous solutions, facilitating its use in biochemical assays and experiments.


H-Leu-Leu-OMe Hydrochloride (CAS 6491-83-4) References

  1. The Outcome of the Cryptococcus neoformans-Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.  |  De Leon-Rodriguez, CM., et al. 2018. J Immunol. 201: 583-603. PMID: 29858266

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

H-Leu-Leu-OMe Hydrochloride, 250 mg

sc-285992
250 mg
$48.00

H-Leu-Leu-OMe Hydrochloride, 1 g

sc-285992A
1 g
$109.00

H-Leu-Leu-OMe Hydrochloride, 5 g

sc-285992B
5 g
$140.00

H-Leu-Leu-OMe Hydrochloride, 25 g

sc-285992C
25 g
$468.00

H-Leu-Leu-OMe Hydrochloride, 100 g

sc-285992D
100 g
$1805.00

is the compounds H-Leu-Leu-OMe Hydrochloride, sc-285992, soluble in DMSO?

Asked by: Anonymous
Thank you for your question. We can not find any solubility data in DMSO. Soluble in methanol (0.15 g/ml).
Answered by: Technical Support
Date published: 2019-04-25

Hello, My name is Hagar from Prof. Ilan Tsarfaty Lab in Tel-Aviv University and i would like pricing for LLOMe (sc-285992) I would love to get the information for your distributor in Israel or how to purchase this item.

Asked by: Hagar
Thank you for your question. Please contact: https://www.scbt.com/scbt/resources/distributors Please choose the country, Israel. Thank you.
Answered by: Technical Support 8
Date published: 2018-01-09

What is the stability of LLOM-HCL ?

Asked by: Eric Wang
Thank you for your question. We don't have reported stability data for this chemical, H-Leu-Leu-OMe Hydrochloride: sc-285992.
Answered by: Technical Support
Date published: 2017-06-14

What is the solubility of this product?

Asked by: hawkeye11
Thank you for your question. H-Leu-Leu-OMe Hydrochloride, sc-285992, is soluble at 0.15 g/ml in MeOH.
Answered by: TechService7
Date published: 2017-01-20
  • y_2026, m_1, d_29, h_17CST
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Rated 5 out of 5 by from Works wellMy fellow tried it and induced significant lysophagy in culture neurons.
Date published: 2017-08-29
Rated 5 out of 5 by from Various publications cite the use of HVarious publications cite the use of H-Leu-Leu-OMe Hydrochloride for its immunosuppressant properties. -SCBT Publication Review
Date published: 2015-04-06
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H-Leu-Leu-OMe Hydrochloride is rated 5.0 out of 5 by 2.
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