Date published: 2026-4-3

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H-Gly-Met-OH (CAS 554-94-9)

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CAS Number:
554-94-9
Molecular Weight:
206.27
Molecular Formula:
C7H14N2O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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H-Gly-Met-OH, also known as glycylmethionine, is a dipeptide composed of the amino acids glycine and methionine. This compound is of particular interest in protein chemistry and enzymology, where it serves as a model substrate to study peptide bond formation and cleavage. Its use in research provides insights into the specificity and mechanism of action of peptidases and proteases, enzymes that are for protein turnover and regulation in living organisms. In addition to its role in enzyme kinetics, H-Gly-Met-OH is utilized in peptide synthesis research to explore coupling reactions and the stability of peptide bonds under various conditions. Moreover, it is involved in studies concerning peptide absorption and metabolism, helping to shed light on the transport mechanisms of di- and tripeptides in cellular membranes. The simplicity of this dipeptide makes it an ideal candidate for fundamental research in peptide chemistry and its applications in the design of peptide-based compounds.


H-Gly-Met-OH (CAS 554-94-9) References

  1. Interaction of cisplatin with methionine- and histidine-containing peptides: competition between backbone binding, macrochelation and peptide cleavage.  |  Hahn, M., et al. 2001. J Biol Inorg Chem. 6: 556-66. PMID: 11472019
  2. Cisplatin mediates selective downstream hydrolytic cleavage of Met-(Gly)(n)-His segments (n=1,2) in methionine- and histidine-containing peptides: the role of ammine loss trans to the initial Pt-S(Met) anchor in facilitating amide hydrolysis.  |  Hohage, O. and Sheldrick, WS. 2006. J Inorg Biochem. 100: 1506-13. PMID: 16806482
  3. High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.  |  Moritz, A., et al. 2019. Sci Immunol. 4: PMID: 31324691

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

H-Gly-Met-OH, 1 g

sc-295082
1 g
$184.00

H-Gly-Met-OH, 5 g

sc-295082A
5 g
$663.00

H-Gly-Met-OH, 25 g

sc-295082B
25 g
$3256.00