Date published: 2026-5-28

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GYKI 53655 hydrochloride (CAS 143692-48-2)

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Alternate Names:
1-(4-Aminophenyl)-3-methylcarbamyl- 4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-ben zodiazepine hydrochloride
Application:
GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist
CAS Number:
143692-48-2
Molecular Weight:
388.85
Molecular Formula:
C19H20N4O3•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist. This compound has also been shown to block GluK3 homomeric receptors (IC50 = 63 µM) and GluK2b(R)/GluK3 heteroreceptors at high concentrations. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

GYKI 53655 hydrochloride, 10 mg

sc-361203
10 mg
$228.00

GYKI 53655 hydrochloride, 50 mg

sc-361203A
50 mg
$966.00