Molecular structure of GW311616 hydrochloride, CAS Number: 197890-44-1
GW311616 hydrochloride (CAS 197890-44-1)
Alternate Names:
GW311616A; (3S,3aS,6aR)-3-Isopropyl-1-(methylsulfonyl)-4-((E)-4-(piperidin-1-yl)but-2-enoyl) hexahydropyrrolo [3,2-b]pyrrol-2(1H)-one
CAS Number:
197890-44-1
Molecular Weight:
434.0
Molecular Formula:
C19H31N3O4S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
GW311616 hydrochloride demonstrates selectivity as an antagonist of the orexin-1 receptor, a key player in the regulation of sleep and wakefulness. This particular compound has found utility in scientific investigations centered around understanding the involvement of the orexin-1 receptor in sleep and wakefulness regulation. Notably, it has been observed to effectively inhibit the effects of orexin-A, a neuropeptide responsible for promoting wakefulness.
GW311616 hydrochloride (CAS 197890-44-1) References
- Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. | Cheung, P., et al. 2021. Nat Immunol. 22: 711-722. PMID: 34017121
Inhibitor of:
cathepsin G, and Neutrophil Elastase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GW311616 hydrochloride, 1 mg | sc-506571 | 1 mg | $94.00 |