Date published: 2026-4-25

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Guvacoline, Hydrobromide (CAS 17210-51-4)

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Alternate Names:
1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Methyl Ester Hydrobromide; 1,2,5,6-Tetrahydronicotinic Acid Methyl Ester Hydrobromide; 3-(Methoxycarbonyl)-1,2,5,6-tetrahydropyridine Hydrobromide
Application:
Guvacoline, Hydrobromide is helpful tool used to identify muscarinic receptors
CAS Number:
17210-51-4
Molecular Weight:
222.07
Molecular Formula:
C7H12BrNO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A helpful tool used to identify muscarinic receptors


Guvacoline, Hydrobromide (CAS 17210-51-4) References

  1. Composition of betel specific chemicals in saliva during betel chewing for the identification of biomarkers.  |  Franke, AA., et al. 2015. Food Chem Toxicol. 80: 241-246. PMID: 25797484
  2. Pilot study of the pharmacokinetics of betel nut and betel quid biomarkers in saliva, urine, and hair of betel consumers.  |  Franke, AA., et al. 2016. Drug Test Anal. 8: 1095-1099. PMID: 26619803
  3. Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester.  |  Wolf-Pflugmann, M., et al. 1989. Arzneimittelforschung. 39: 539-44. PMID: 2757669
  4. Analysis of Alkaloids in Areca Nut-Containing Products by Liquid Chromatography-Tandem Mass Spectrometry.  |  Jain, V., et al. 2017. J Agric Food Chem. 65: 1977-1983. PMID: 28190359
  5. Sub-chronic toxicity study of arecae semen aqueous extract in Wistar rats.  |  Lin, Q., et al. 2018. J Ethnopharmacol. 215: 176-183. PMID: 28847753
  6. Chemical Markers for Short- and Long-Term Areca Nut Exposure.  |  Franke, AA., et al. 2020. Subst Use Misuse. 55: 1395-1402. PMID: 31244365
  7. Distinct phenolic, alkaloid and antioxidant profile in betel quids from four regions of Indonesia.  |  Sari, EF., et al. 2020. Sci Rep. 10: 16254. PMID: 33004929
  8. Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor.  |  Flöser, A., et al. 2021. Elife. 10: PMID: 34851820
  9. Salivary Areca and tobacco alkaloids for bioverification in the Betel Nut Intervention Trial.  |  Franke, AA., et al. 2023. Drug Test Anal. 15: 58-65. PMID: 36057968
  10. Metabolomic Profile of Indonesian Betel Quids.  |  Zhang, P., et al. 2022. Biomolecules. 12: PMID: 36291678

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Guvacoline, Hydrobromide, 10 mg

sc-211576
10 mg
$330.00