Date published: 2026-4-25

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Guanylyl-5′-imidodiphosphate, Tetralithium Salt (CAS 64564-03-0)

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Alternate Names:
GMP-PNP, 4Li
CAS Number:
64564-03-0
Molecular Weight:
545.9
Molecular Formula:
C10H13N6O13P34Li
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Guanylyl-5′-imidodiphosphate, Tetralithium Salt is the preferred GTP analog for activation of ADP-ribosylation factor. Non-hydrolyzable GTP analog that is used for the study of GTP-dependent enzymes. Guanylyl-5′-imidodiphosphate, Tetralithium Salt binds tightly to G-proteins and causes irreversible activation. May be useful in studies requiring presaturation of GTP-binding sites.


Guanylyl-5′-imidodiphosphate, Tetralithium Salt (CAS 64564-03-0) References

  1. Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones.  |  Holohean, AM. and Hackman, JC. 2004. Br J Pharmacol. 143: 351-60. PMID: 15339859
  2. ADP-ribosylation of G proteins with pertussis toxin.  |  Kopf, GS. and Woolkalis, MJ. 1991. Methods Enzymol. 195: 257-66. PMID: 1903490
  3. Differential effects of guanine nucleotides on kainic acid binding and on adenylate cyclase activity in chick optic tectum.  |  Paz, MM., et al. 1994. FEBS Lett. 355: 205-8. PMID: 7982502
  4. G protein-coupled receptors mediate a fast excitatory postsynaptic current in CA3 pyramidal neurons in hippocampal slices.  |  Pozzo Miller, LD., et al. 1995. J Neurosci. 15: 8320-30. PMID: 8613765

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Guanylyl-5′-imidodiphosphate, Tetralithium Salt, 25 mg

sc-221698
25 mg
$1230.00