Guanylin (human) (CAS 183200-12-6)
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Guanylin (human) is primarily investigated for its role in regulating salt and water balance through its involvement in the activation of the guanylate cyclase-C receptor in intestinal epithelial cells. Research on guanylin (human) often focuses on understanding its molecular mechanisms and its effects on electrolyte homeostasis. This peptide is also studied in the context of its influence on intestinal fluid dynamics, which can impact nutrient absorption and secretion processes. Additionally, guanylin (human) is of interest in studies examining the regulation of blood pressure and intestinal motility. Researchers explore the synthesis and secretion pathways of guanylin (human) to gain deeper insights into its physiological functions and potential implications in electrolyte balance.
Guanylin (human) (CAS 183200-12-6) References
- Effects of guanylin and uroguanylin on rat jejunal fluid and electrolyte transport: comparison with heat-stable enterotoxin. | Ieda, H., et al. 1999. Regul Pept. 79: 165-71. PMID: 10100931
- Expression of guanylin is downregulated in mouse and human intestinal adenomas. | Steinbrecher, KA., et al. 2000. Biochem Biophys Res Commun. 273: 225-30. PMID: 10873591
- Guanylin family: new intestinal peptides regulating electrolyte and water homeostasis. | Nakazato, M. 2001. J Gastroenterol. 36: 219-25. PMID: 11324723
- Human guanylin: cDNA isolation, structure, and activity. | Wiegand, RC., et al. 1992. FEBS Lett. 311: 150-4. PMID: 1327879
- Guanylin: an endogenous activator of intestinal guanylate cyclase. | Currie, MG., et al. 1992. Proc Natl Acad Sci U S A. 89: 947-51. PMID: 1346555
- Precursor structure, expression, and tissue distribution of human guanylin. | de Sauvage, FJ., et al. 1992. Proc Natl Acad Sci U S A. 89: 9089-93. PMID: 1409606
- Characterization of immunological cross-reactivity between enterotoxigenic Escherichia coli heat-stable toxin and human guanylin and uroguanylin. | Taxt, AM., et al. 2014. Infect Immun. 82: 2913-22. PMID: 24778111
- Computational analyses and prediction of guanylin deleterious SNPs. | Porto, WF., et al. 2015. Peptides. 69: 92-102. PMID: 25899674
- Analysis of the human guanylin gene and the processing and cellular localization of the peptide. | Hill, O., et al. 1995. Proc Natl Acad Sci U S A. 92: 2046-50. PMID: 7892222
- The circulating bioactive form of human guanylin is a high molecular weight peptide (10.3 kDa). | Kuhn, M., et al. 1993. FEBS Lett. 318: 205-9. PMID: 8095028
- Characterization of human uroguanylin: a member of the guanylin peptide family. | Kita, T., et al. 1994. Am J Physiol. 266: F342-8. PMID: 8141334
- Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. | Nokihara, K., et al. 1997. Regul Pept. 70: 111-20. PMID: 9272623
- Matrix-assisted laser desorption/ionisation mass spectrometry guided purification of human guanylin from blood ultrafiltrate. | Schrader, M., et al. 1997. J Chromatogr A. 776: 139-45. PMID: 9286088
- Effect and distribution of intravenously injected 125I-guanylin in rat kidney examined by high-resolution light microscopic radioautography. | Furuya, S., et al. 1997. Anat Embryol (Berl). 196: 185-93. PMID: 9310311
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Guanylin (human), 100 µg | sc-203066 | 100 µg | $133.00 | |||
Guanylin (human), 500 µg | sc-203066B | 500 µg | $571.00 |