Guanosine 5′-(tetrahydrogen triphosphate) Sodium Salt (CAS 24905-71-3)

Guanosine 5′-(tetrahydrogen triphosphate) Sodium Salt, known as GTP Sodium Salt, is a nucleotide derivative extensively utilized in biochemical and molecular biology research. This compound, structurally composed of the nucleoside guanosine bound to three phosphate groups (triphosphate), plays a pivotal role in various cellular processes, particularly those involving signal transduction and energy transfer. In its sodium salt form, GTP becomes more soluble in aqueous solutions, facilitating its use in experimental applications. The primary mechanism of action of Guanosine 5′-(tetrahydrogen triphosphate) Sodium Salt involves its function as a substrate for the synthesis of RNA during transcription, as well as its role as an energy source and a signaling molecule in protein synthesis, particularly in the formation of GTPase enzymes. These enzymes are in signal transduction pathways, where they act as molecular switches. Guanosine 5′-(tetrahydrogen triphosphate) Sodium Salt is instrumental in the study of G-protein coupled receptors (GPCRs), which are a large family of cell surface receptors that play a key role in cell communication and various physiological processes. Additionally, it is vital in research focused on the understanding of the mechanics of translation in ribosomes and the role of GTPases in intracellular transport and cellular growth. Its versatility in molecular biology makes it a key reagent in the exploration of fundamental cellular mechanisms and the understanding of complex signaling pathways.