Molecular structure of Guanosine 5′-diphosphate disodium salt, CAS Number: 7415-69-2
Guanosine 5′-diphosphate disodium salt (CAS 7415-69-2)
Alternate Names:
5′-GDP-Na2
CAS Number:
7415-69-2
Purity:
≥95%
Molecular Weight:
487.16
Molecular Formula:
C10H13N5O11P2•2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Guanosine-5′-diphosphate disodium salt (GDP) is a vital nucleotide that plays a role in cellular metabolism and the generation of energy. It is an indispensable member of the nucleoside triphosphate family and participates in a diverse array of biochemical reactions, including the synthesis of DNA and RNA, protein synthesis, and energy transfer. Furthermore, Guanosine-5′-diphosphate disodium salt is a fundamental component of the nucleotide cycle, which upholds the equilibrium between energy production and storage within cells. Its involvement extends to regulating gene expression, facilitating signal transduction, and governing metabolic pathways. Additionally, Guanosine-5′-diphosphate disodium salt is instrumental in maintaining cell structure and function, as well as modulating cell growth and differentiation.
Guanosine 5′-diphosphate disodium salt (CAS 7415-69-2) References
- RNA displacement and resolution of the transcription bubble during transcription by T7 RNA polymerase. | Jiang, M., et al. 2004. Mol Cell. 15: 777-88. PMID: 15350221
- FRET-based direct and continuous monitoring of human fucosyltransferases activity: an efficient synthesis of versatile GDP-L-fucose derivatives from abundant D-galactose. | Maeda, T. and Nishimura, S. 2008. Chemistry. 14: 478-87. PMID: 17929334
- Hydrogen-bond-guided self-assembly of nucleotides on a receptor-array surface. | Turygin, DS., et al. 2010. Chemistry. 16: 10560-8. PMID: 20648485
- An efficient approach to the discovery of potent inhibitors against glycosyltransferases. | Hosoguchi, K., et al. 2010. J Med Chem. 53: 5607-19. PMID: 20684602
- Palladium(II) complexes of tridentate bis(benzazole) ligands: Structural, substitution kinetics, DNA interactions and cytotoxicity studies. | Omondi, RO., et al. 2020. J Inorg Biochem. 210: 111156. PMID: 32645652
- Development of Facile and Selective Fluorescent Probe for Physiological Phosphates based on Aggregation-induced Emission. | Jiao, Z., et al. 2020. J Fluoresc. 30: 1197-1202. PMID: 32700171
- Role of π-conjugation on the coordination behaviour, substitution kinetics, DNA/BSA interactions, and in vitro cytotoxicity of carboxamide palladium(II) complexes. | Omondi, RO., et al. 2021. Dalton Trans. 50: 8127-8143. PMID: 34027534
- Assay of GTPγS Binding in Autoradiography. | Gabaglio, M., et al. 2023. Methods Mol Biol. 2576: 181-188. PMID: 36152186
- Synthesis, substitution kinetics, DNA/BSA binding and cytotoxicity of tridentate N^E^N (E = NH, O, S) pyrazolyl palladium(II) complexes. | Omondi, RO., et al. 2022. J Biol Inorg Chem. 27: 653-664. PMID: 36197522
- Enhancement of inhibition rate of antibiotic against bacteria by molecularly imprinted nanoparticles targeting alarmone nucleotides as antibiotic adjuvants. | Chen, Y., et al. 2022. J Mater Chem B. 10: 9438-9445. PMID: 36321529
- Bisphosphonate modification in tetraphosphate 5'mRNA cap analogs – synthesis and biochemical properties | Anna Rydzik, Joanna Zuberek, Joanna Kowalska, Edward Darżynkiewicz and Jacek Jemielity. 2008. Collection Symposium Series., 10,: 444-448.
- A robust OFF-ON fluorescent biosensor for detection and clearance of bacterial endotoxin by specific peptide based aggregation induced emission | YY Tang, A Kang, XT Yang, LY Hu, YY Tang… - Sensors and Actuators B …, 2020 - Elsevier. February 2020,. Sensors and Actuators B: Chemical. Volume 304, 1: 127300.
- Unexpected catalytic activity of Pd(II)-coordinated nucleotides in hydrogenation reduction | T Zou, Y Han, X Li, W Li, J Zhang, Y Fu - Colloids and Surfaces A …, 2019 - Elsevier. 5 January 2019,. Colloids and Surfaces A: Physicochemical and Engineering Aspects. Volume 560,: Pages 344-351.
Inhibitor of:
PNPase.Activator of:
DGK-γ, eIF5B, FucT-VII, Gpa1, LET-60 RAS, LSm8, Mog1p, NTF2, Rab 17, Rab 34, Rab 39A, RASGEF1B, SerpinB8, Tuba, and UCP2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Guanosine 5′-diphosphate disodium salt, 100 mg | sc-211574 | 100 mg | $206.00 | |||
Guanosine 5′-diphosphate disodium salt, 500 mg | sc-211574A | 500 mg | $698.00 |