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Guanosine-3′,5′-cyclic Monophosphothioate, Sp-Isomer sodium salt (CAS 86562-10-9)

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Application:
Guanosine-3′,5′-cyclic Monophosphothioate, Sp-Isomer sodium salt is an activator of cGMP-dependent protein kinase
CAS Number:
86562-10-9
Molecular Weight:
383.3
Molecular Formula:
C10H11N5O6SP•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Guanosine-3′,5′-cyclic Monophosphothioate, Sp-Isomer sodium salt is a metabolically resistant activator of cGMP-dependent protein kinases (PKGs). Guanosine-3′,5′-cyclic Monophosphothioate, Sp-Isomer sodium salt has low membrane permeability.


Guanosine-3′,5′-cyclic Monophosphothioate, Sp-Isomer sodium salt (CAS 86562-10-9) References

Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3′,5′- monophosphorothioates: E. Butt, et al.; FEBS Lett. 263, 47 (1990) Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase: S.L. Archer, et al.; PNAS 91, 7583 (1994) Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp)-8-bromo-PET-cyclic GMPS: E. Butt, et al.; Br. J. Pharmacol. 116, 3110 (1995)

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Guanosine-3′,5′-cyclic Monophosphothioate, Sp-Isomer sodium salt, 500 µg

sc-203065
500 µg
$200.00

Guanosine-3′,5′-cyclic Monophosphothioate, Sp-Isomer sodium salt, 1 mg

sc-203065A
1 mg
$400.00