Molecular structure of Guanosine, CAS Number: 118-00-3
Guanosine (CAS 118-00-3)
Alternate Names:
9-(β-D-Ribofuranosyl)guanine; Guanine-9-β-D-ribofuranoside
Application:
Guanosine is Guanosine is a purine nucleoside.
CAS Number:
118-00-3
Purity:
≥99%
Molecular Weight:
283.24
Molecular Formula:
C10H13N5O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Guanosine, a purine nucleoside, consists of guanine and ribose, and it plays a fundamental role in various biological processes. As a component of nucleic acids like DNA and RNA, guanosine is integral to their structure and function. It is also present in certain proteins and small molecules. Moreover, guanosine serves as a intermediate in synthesizing numerous compounds, including purine nucleotides and guanidine derivatives. The significance of guanosine extends to diverse biological functions such as energy metabolism, signal transduction, and gene regulation. As a nucleoside, guanosine combines a purine base (guanine) with a sugar (ribose). When incorporated into nucleic acids, guanosine acts as a template for the formation of base pairs. This process enables the creation of double-stranded DNA and RNA molecules, pivotal for gene expression and various biological processes to occur.
Guanosine (CAS 118-00-3) References
- Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury. | Kelly, KJ., et al. 2001. J Clin Invest. 108: 1291-8. PMID: 11696573
- Anticonvulsant effect of GMP depends on its conversion to guanosine. | Soares, FA., et al. 2004. Brain Res. 1005: 182-6. PMID: 15044076
- Intriguing mass spectrometric behavior of guanosine under low energy collision-induced dissociation: H2O adduct formation and gas-phase reactions in the collision cell. | Tuytten, R., et al. 2005. J Am Soc Mass Spectrom. 16: 1291-304. PMID: 15979336
- Solventless protocol for efficient bis-N-boc protection of adenosine, cytidine, and guanosine derivatives. | Sikchi, SA. and Hultin, PG. 2006. J Org Chem. 71: 5888-91. PMID: 16872168
- Pharmacokinetics of guanosine in rats following intravenous or intramuscular administration of a 1:1 mixture of guanosine and acriflavine, a potential antitumor agent. | Shin, DH., et al. 2008. Arch Pharm Res. 31: 1347-53. PMID: 18958427
- Electrochemical behaviors of guanosine on carbon ionic liquid electrode and its determination. | Sun, W., et al. 2009. Talanta. 78: 695-9. PMID: 19269414
- Mechanisms involved in the antinociception induced by systemic administration of guanosine in mice. | Schmidt, AP., et al. 2010. Br J Pharmacol. 159: 1247-63. PMID: 20132210
- Absolute configurations and stability of cyclic guanosine mono-adducts with glyoxal and methylglyoxal. | Lai, C., et al. 2011. Chirality. 23: 487-94. PMID: 21500285
- Evidence for the existence of a specific g protein-coupled receptor activated by guanosine. | Volpini, R., et al. 2011. ChemMedChem. 6: 1074-80. PMID: 21500353
- Highly fluorescent guanosine mimics for folding and energy transfer studies. | Dumas, A. and Luedtke, NW. 2011. Nucleic Acids Res. 39: 6825-34. PMID: 21551219
- Formation and characterization of covalent guanosine adducts with electrochemistry-liquid chromatography-mass spectrometry. | Plattner, S., et al. 2012. J Chromatogr B Analyt Technol Biomed Life Sci. 883-884: 198-204. PMID: 22000962
- Identifying guanosine self assembly at natural isotopic abundance by high-resolution 1H and 13C solid-state NMR spectroscopy. | Webber, AL., et al. 2011. J Am Chem Soc. 133: 19777-95. PMID: 22034827
- Supramolecular arrangement of guanosine/5-guanosine monophosphate binary mixtures studied by methods of circular dichroism. | Novotná, J., et al. 2012. Chirality. 24: 432-8. PMID: 22517502
- Two-step, one-pot synthesis of inosine, guanosine, and 2'-deoxyguanosine O6-ethers via intermediate O6-(benzotriazol-1-yl) derivatives. | Kokatla, HP. and Lakshman, MK. 2012. Curr Protoc Nucleic Acid Chem. Chapter 1: Unit1.26. PMID: 22700333
- The hot water extract and active components nicotinamide and guanosine of the leather carp Cyprinus carpio nudis improve exercise performance in mice. | Harwanto, D., et al. 2019. J Food Biochem. 43: e13004. PMID: 31368180
Activator of:
γ-GCSc, 2,2,7-trimethylguanosine, 2610528E23Rik, adenosine deaminase, ADSL, CD39L1, CNT1, CNT2, CNT3, Cypin, DDX10, ENT2, ENT4, Influenza B, NPR-B, Olfr467, Olfr469, Olfr513, Olfr514, Olfr996, Olfr998, PANK1, PNP, PUS7, RBKS, RBPMS2, Ribosomal Protein L28, RmlB, UCK1, and WDR92.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Guanosine, 5 g | sc-218575 | 5 g | $39.00 | |||
Guanosine, 25 g | sc-218575A | 25 g | $49.00 | |||
Guanosine, 250 g | sc-218575B | 250 g | $82.00 | |||
Guanosine, 1 kg | sc-218575C | 1 kg | $245.00 | |||
Guanosine, 5 kg | sc-218575D | 5 kg | $1081.00 |