Guanethidine sulfateAn antihypertensive and antiglaucoma

Guanethidine sulfate (CAS 645-43-2)

Guanethidine sulfate | CAS 645-43-2 is rated 5.0 out of 5 by 1.
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Synonym: N-[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine Sulfate
Application: An antihypertensive and antiglaucoma
CAS Number: 645-43-2
Purity: ≥99%
Molecular Weight: 296.39
Molecular Formula: C10H22N4•H2SO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Guanethidine sulfate is an antihypertensive and antiglaucoma.


References

Al-Shora, H., et al.: Int. J. Pharm., 47, 209 (1988), Golander, Y., et al.: J. Pharm. Sci., 77, 902 (1988),

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (1:15).
Storage :
Store at -20° C
Melting Point :
250° C (dec.)
Boiling Point :
345.6° C at 760 mmHg (Predicted)
pK Values :
pKb: 13.36 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
MF3150000
PubChem CID :
86471
MDL Number :
MFCD00035403
EC Number :
200-452-0
SMILES :
C1CCCN(CCC1)CCN=C(N)N.OS(=O)(=O)O

Download SDS (MSDS)

Certificate of Analysis

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Guanethidine sulfate  Product Citations

See how others have used Guanethidine sulfate. Click on the entry to view the PubMed entry .

Citations 1 to 4 of 4 total

PMID: # 26499847  Zhang, J. et al. 2015. Sci Rep. 5: 15503.

PMID: # 24929853  Reho, JJ. et al. 2014. Am. J. Physiol. Heart Circ. Physiol. 307: H563-73.

PMID: # 24731096  Gil-Lozano, M. et al. 2014. Endocrinology. 155: 2511-23.

PMID: # 23761902  Longo, G. et al. 2013. J. Neurosci. 33: 10066-74.

Citations 1 to 4 of 4 total

What are the storage conditions?

Asked by: SCchem16
Thank you for your question. This chemical, Guanethidine sulfate (CAS 645-43-2), is hygroscopic. We recommend it be stored at -20ºc under inert atmosphere.
Answered by: Chemical Support 2
Date published: 2017-03-24
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Rated 5 out of 5 by from Guanethidine inhibited the sustained phase Guanethidine inhibited the sustained phase of calcium-induced EFS-evoked contractions by reducing ATP release in rabbit vas deferens. -SCBT Publication Review
Date published: 2015-06-25
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