Date published: 2025-11-22

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GTAM8 Marker Antibody (B43.8): sc-59195

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Datasheets
  • GTAM8 Marker Antibody (B43.8) is a mouse monoclonal IgG1 provided at 500 µl supernatant
  • raised against GTAM8 of human origin
  • recommended for detection of GTAM8 of human origin by WB, IF and IHC(P)
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GTAM8 Marker Antibody (B43.8). This work is in progress.

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    GTAM8 Marker Antibody (B43.8) is a mouse monoclonal IgG1 antibody that detects GTAM8 of human origin by western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Anti-GTAM8 antibody (B43.8) is available in a non-conjugated form, providing flexibility for various experimental needs. GTAM8, or gastrointestinal tumor-associated marker 8, plays a crucial role in identifying gastric carcinoma, a cancer that can arise in any part of the stomach and metastasize to other organs such as the esophagus and small intestine. GTAM8 expression occurs in various tissues, including pancreas, lung, colon, ovary, prostate, and gastric carcinomas, making GTAM8 a valuable biomarker for malignancy. Understanding GTAM8 structure is essential, as this glycoprotein undergoes post-translational modifications, including glycosylation, which can influence stability, localization, and protein interactions. These modifications affect GTAM8 function in tumor biology by impacting cell signaling pathways and immune response to cancer cells. Accurate detection of GTAM8 using GTAM8 monoclonal antibody (B43.8) can aid in early diagnosis of gastric carcinoma and help differentiate between benign and malignant conditions, ultimately contributing to more effective treatment strategies.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    GTAM8 Marker Antibody (B43.8) References:

    1. Sialosyl-Tn antigen. Its distribution in normal human tissues and expression in adenocarcinomas.  |  Yonezawa, S., et al. 1992. Am J Clin Pathol. 98: 167-74. PMID: 1510031
    2. Characterization of new pancreatic cancer-reactive monoclonal antibodies directed against purified mucin.  |  Ho, JJ., et al. 1991. Cancer Res. 51: 372-80. PMID: 1703039
    3. Relationship of pancreatic cancer apomucin to mammary and intestinal apomucins.  |  Byrd, JC., et al. 1991. Cancer Res. 51: 1026-33. PMID: 1988113
    4. Cancer-associated alterations of blood group antigen expression in the human pancreas.  |  Itzkowitz, SH., et al. 1987. J Natl Cancer Inst. 79: 425-34. PMID: 2442445
    5. Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors.  |  Hilkens, J., et al. 1984. Int J Cancer. 34: 197-206. PMID: 6206003
    6. Monoclonal antibody directed against colon cancer mucin has high specificity for malignancy.  |  Siddiki, B., et al. 1993. Int J Cancer. 54: 467-74. PMID: 7685327
    7. Immunohistochemical study of mucin carbohydrates and core proteins in human pancreatic tumors.  |  Osako, M., et al. 1993. Cancer. 71: 2191-9. PMID: 8384065

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    GTAM8 Marker Antibody (B43.8)

    sc-59195
    500 µl supernatant
    $316.00