group XIIA sPLA2 Antibody (SP-34): sc-134352
- group XIIA sPLA2 Antibody (SP-34) is a mouse monoclonal IgG1 κ group XIIA sPLA2 antibody provided at 100 µg/ml
- raised against recombinant group XIIA sPLA2 protein of human origin
- recommended for detection of group XIIA sPLA2 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for group XIIA sPLA2 Antibody (SP-34). This work is in progress.
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Group XIIA sPLA2 Antibody (SP-34) is a mouse monoclonal IgG1 kappa light chain antibody that detects the group XIIA sPLA2 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-group XIIA sPLA2 antibody (SP-34) is available as a non-conjugated monoclonal isotype antibody. Group XIIA sPLA2, also known as GXII, ROSSY, PLA2G12, or PLA2G12A, is a 189 amino acid secreted protein that plays a crucial role in lipid metabolism by hydrolyzing phospholipids to release arachidonic acid, a precursor for various eicosanoids involved in inflammatory responses and other physiological processes. Group XIIA sPLA2 is predominantly expressed in tissues such as the heart, skeletal muscle, kidney, liver, and pancreas, highlighting its importance in maintaining cellular functions and responding to stress. Group XIIA sPLA2 has a unique structure and relatively low specific activity compared to other secreted phospholipases A2, which may influence its regulatory role in lipid signaling pathways. Group XIIA sPLA2′s ability to interact with specific proteins in these pathways further underscores its significance in both physiological and pathological contexts, making Group XIIA sPLA2 a valuable target for research in inflammation and metabolic disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
group XIIA sPLA2 Antibody (SP-34) | sc-134352 | 100 µg/ml | $339.00 |