Molecular structure of GR 79236, CAS Number: 124555-18-6
GR 79236 (CAS 124555-18-6)
Alternate Names:
N-[(1S, trans)-2-Hydroxycyclopentyl]adenosine
Application:
GR 79236 is an Adenosine A1-R agonist
CAS Number:
124555-18-6
Molecular Weight:
351.36
Molecular Formula:
C15H21N5O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
GR 79236 has been shown to be an adenosine A receptor agonist.
GR 79236 (CAS 124555-18-6) References
- The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig. | Louttit, JB., et al. 1999. J Cardiovasc Pharmacol. 33: 285-91. PMID: 10028938
- The effect of body temperature on myocardial protection conferred by ischaemic preconditioning or the selective adenosine A1 receptor agonist GR79236, in an anaesthetized rabbit model of myocardial ischaemia and reperfusion. | Sheldrick, A., et al. 1999. Br J Pharmacol. 128: 385-95. PMID: 10510449
- Adenosine A1 receptor agonists inhibit trigeminovascular nociceptive transmission. | Goadsby, PJ., et al. 2002. Brain. 125: 1392-401. PMID: 12023327
- Study of an adenosine A1 receptor agonist on trigeminally evoked dural blood vessel dilation in the anaesthetized rat. | Honey, AC., et al. 2002. Cephalalgia. 22: 260-4. PMID: 12100087
- Lack of effect of the adenosine A1 receptor agonist, GR79236, on capsaicin-induced CGRP release in anaesthetized pigs. | Arulmani, U., et al. 2005. Cephalalgia. 25: 1082-90. PMID: 16232161
- Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction. | Sneyd, JR., et al. 2007. Br J Anaesth. 98: 672-6. PMID: 17416906
- Characterization of the prejunctional adenosine receptors in the rat anococcygeus muscle. | Coates, J., et al. 1994. J Pharm Pharmacol. 46: 906-10. PMID: 7897597
- The effects of GR79236 on plasma fatty acid concentrations, heart rate and blood pressure in the conscious rat. | Gardner, CJ., et al. 1994. Eur J Pharmacol. 257: 117-21. PMID: 8082691
- Characterization of the adenosine receptor mediating contraction in rat colonic muscularis mucosae. | Reeves, JJ., et al. 1993. Br J Pharmacol. 110: 1255-9. PMID: 8298815
- Suppression of non-esterified fatty acids and triacylglycerol in experimental animals by the adenosine analogue GR79236. | Strong, P., et al. 1993. Clin Sci (Lond). 84: 663-9. PMID: 8334813
- Functional characterization of three adenosine receptor types. | Gurden, MF., et al. 1993. Br J Pharmacol. 109: 693-8. PMID: 8358566
- In vitro effect of adenosine agonist GR79236 on the insulin sensitivity of glucose utilisation in rat soleus and human rectus abdominus muscle. | Webster, JM., et al. 1996. Biochim Biophys Acta. 1316: 109-13. PMID: 8672547
- Short-term metabolic and haemodynamic effects of GR79236 in normal and fructose-fed rats. | Qu, X., et al. 1997. Eur J Pharmacol. 338: 269-76. PMID: 9424021
- Adenosine A1 receptor agonist GR79236 suppresses apnea during all sleep stages in the rat. | Carley, DW., et al. 1997. Sleep. 20: 1093-8. PMID: 9493917
Inhibitor of:
A1.Activator of:
Adenosine A1-R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GR 79236, 10 mg | sc-361197 | 10 mg | $235.00 | |||
GR 79236, 50 mg | sc-361197A | 50 mg | $999.00 |