GPR157 Antibody (G-5): sc-398916
- GPR157 Antibody (G-5) is a mouse monoclonal IgG1 κ GPR157 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 197-220 within a cytoplasmic domain of GPR157 of human origin
- GPR157 Antibody (G-5) is recommended for detection of GPR157 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-GPR157 Antibody (G-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GPR157 Antibody (G-5). This work is in progress.
GPR157 Antibody (G-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects GPR157 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GPR157 monoclonal antibody (G-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GPR157 is a 335 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR2 family, known for mediating various physiological processes. GPR157 resides in the plasma membrane, where this protein plays a crucial role in signal transduction. Through strategic positioning at the cell surface, GPR157 interacts with extracellular signaling molecules, including hormones and neurotransmitters, facilitating signal transmission that influences cellular responses. GPR157 encoding gene is located on human chromosome 1p36.23, a region associated with several genetic disorders, including familial adenomatous polyposis and schizophrenia, highlighting GPR157′s importance in normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GPR157 Antibody (G-5) References:
- Two novel polymorphic sequences in the glucocerebrosidase gene region enhance mutational screening and founder effect studies of patients with Gaucher disease. | Lau, EK., et al. 1999. Hum Genet. 104: 293-300. PMID: 10369158
- The G protein-coupled receptor repertoires of human and mouse. | Vassilatis, DK., et al. 2003. Proc Natl Acad Sci U S A. 100: 4903-8. PMID: 12679517
- Functional assays for identifying ligands at orphan G protein-coupled receptors. | Szekeres, PG. 2002. Recept Channels. 8: 297-308. PMID: 12690957
- Constitutively activated G protein-coupled receptors: a novel approach to CNS drug discovery. | Menzaghi, F., et al. 2002. Curr Drug Targets CNS Neurol Disord. 1: 105-21. PMID: 12769637
- Exclusion of an extracolonic disease modifier locus on chromosome 1p33-36 in a large Swiss familial adenomatous polyposis kindred. | Plasilova, M., et al. 2004. Eur J Hum Genet. 12: 365-71. PMID: 14735163
- Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. | Oliveira, SA., et al. 2005. Am J Hum Genet. 77: 252-64. PMID: 15986317
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. | Daub, H., et al. 2008. Mol Cell. 31: 438-48. PMID: 18691976
- Analysis of the vitreous membrane in a case of type 1 Stickler syndrome. | Yokoi, T., et al. 2009. Graefes Arch Clin Exp Ophthalmol. 247: 715-8. PMID: 19089441
- Present perspectives on the automated classification of the G-protein coupled receptors (GPCRs) at the protein sequence level. | Davies, MN., et al. 2011. Curr Top Med Chem. 11: 1994-2009. PMID: 21470173
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GPR157 Antibody (G-5) | sc-398916 | 200 µg/ml | $322.00 | |||
GPR157 Antibody (G-5) AC | sc-398916 AC | 500 µg/ml, 25% agarose | $424.00 | |||
GPR157 Antibody (G-5) HRP | sc-398916 HRP | 200 µg/ml | $322.00 | |||
GPR157 Antibody (G-5) FITC | sc-398916 FITC | 200 µg/ml | $336.00 | |||
GPR157 Antibody (G-5) PE | sc-398916 PE | 200 µg/ml | $349.00 | |||
GPR157 Antibody (G-5) Alexa Fluor® 488 | sc-398916 AF488 | 200 µg/ml | $364.00 | |||
GPR157 Antibody (G-5) Alexa Fluor® 546 | sc-398916 AF546 | 200 µg/ml | $364.00 | |||
GPR157 Antibody (G-5) Alexa Fluor® 594 | sc-398916 AF594 | 200 µg/ml | $364.00 | |||
GPR157 Antibody (G-5) Alexa Fluor® 647 | sc-398916 AF647 | 200 µg/ml | $364.00 | |||
GPR157 Antibody (G-5) Alexa Fluor® 680 | sc-398916 AF680 | 200 µg/ml | $364.00 | |||
GPR157 Antibody (G-5) Alexa Fluor® 790 | sc-398916 AF790 | 200 µg/ml | $364.00 | |||
GPR157 (G-5) Neutralizing Peptide | sc-398916 P | 100 µg/0.5 ml | $69.00 |