GOLPH3 Antibody (905CT9.1.1): sc-517333

GOLPH3 Antibody (905CT9.1.1) is a mouse monoclonal IgG1 antibody that detects GOLPH3 protein of human origin by western blotting (WB) and immunoprecipitation (IP). Anti-GOLPH3 antibody (905CT9.1.1) is available as a non-conjugated format. GOLPH3, also known as golgi phosphoprotein 3, GOPP1, GPP34, or MIDAS, is a 298 amino acid protein that plays a crucial role in regulating protein trafficking within the Golgi apparatus, a vital cellular organelle responsible for processing and packaging proteins. GOLPH3 localizes to both cytoplasm and Golgi stack membrane, suggesting an integral role in maintaining proper protein flow through the secretory pathway, essential for cellular function and communication. Dysregulation of GOLPH3 has been implicated in various diseases, including cancer, where altered protein transport and secretion may contribute to tumor growth and metastasis. GOLPH3 undergoes post-translational modifications, including phosphorylation, which influences activity and protein interactions. GOLPH3 gene resides on human chromosome 5, a chromosome associated with several genetic disorders, highlighting GOLPH3′s importance in normal physiology and disease states.

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GOLPH3 Antibody (905CT9.1.1) References:

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