GOLGA7 Antibody (NO-2): sc-101278

GOLGA7 Antibody (NO-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects GOLGA7 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-GOLGA7 antibody (NO-2) is available as a non-conjugated format. GOLGA7, also known as Golgin subfamily A member 7 or GCP16, is a multi-pass membrane protein that plays a crucial role in the structure and function of the Golgi apparatus. GOLGA7 is essential for maintaining Golgi integrity and is involved in protein transport from the Golgi to the cell surface. GOLGA7 undergoes palmitoylation on two cysteine residues, a post-translational modification vital for interaction with golgin 160 and proper Golgi localization. Additionally, GOLGA7 forms a complex with ZDHHC9, functioning as a Ras palmitoyltransferase, necessary for H-Ras and N-Ras protein palmitoylation. This palmitoylation is critical for Ras protein trafficking from the Golgi to the plasma membrane, highlighting GOLGA7′s significant role in cellular signaling and protein transport.

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GOLGA7 Antibody (NO-2) References:

1. Identification and characterization of GCP16, a novel acylated Golgi protein that interacts with GCP170.  |  Ohta, E., et al. 2003. J Biol Chem. 278: 51957-67. PMID: 14522980
2. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras.  |  Swarthout, JT., et al. 2005. J Biol Chem. 280: 31141-8. PMID: 16000296
3. Protein palmitoylation by a family of DHHC protein S-acyltransferases.  |  Mitchell, DA., et al. 2006. J Lipid Res. 47: 1118-27. PMID: 16582420
4. Chondrocyte secreted CRTAC1: a glycosylated extracellular matrix molecule of human articular cartilage.  |  Steck, E., et al. 2007. Matrix Biol. 26: 30-41. PMID: 17074475
5. FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis.  |  Elbauomy Elsheikh, S., et al. 2007. Breast Cancer Res. 9: R23. PMID: 17397528
6. Differential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroups.  |  Mansilla, F., et al. 2007. Br J Cancer. 96: 1896-903. PMID: 17519897
7. Protein lipidation.  |  Nadolski, MJ. and Linder, ME. 2007. FEBS J. 274: 5202-10. PMID: 17892486

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GOLGA7 Antibody (NO-2) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-GOLGA7 Antibody (NO-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GOLGA7 Antibody (NO-2) Specifications

Alternate Product Name: GOLGA7

Product Clone Name: NO-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-138

Epitope Target: GOLGA7

Epitope Species: human

Product Reactivity/Detection: GOLGA7

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for GOLGA7 Antibody (NO-2): N/A