Molecular structure of Glycyrrhizin Acid Ammonium Salt, CAS Number: 53956-04-0
Glycyrrhizin Acid Ammonium Salt (CAS 53956-04-0)
See product citations (4)
Alternate Names:
Monoammonium glycyrrhizinate
Application:
Glycyrrhizin Acid Ammonium Salt is a potent anti-viral agent
CAS Number:
53956-04-0
Purity:
≥97%
Molecular Weight:
839.97
Molecular Formula:
C42H62O16•NH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Glycyrrhizin Acid Ammonium salt is a constituent of the licorice root that has vital anti-viral activities that have been shown to inhibit the expression of 11beta-HSD2 (11beta-hydroxysteroid dehydrogenase type 2) via an indirect mechanism. Studies suggest that nitric oxide production is amplified in the macrophage cell line RAW264-7 and IFN-gamma activated-macrophages. Furthermore, Glycyrrhizin acid stimulates the tumor cell killing effects of IFN -gamma activated-macrophages. In addition the expression of COX-2 (cyclooxygenase-2) and NOS2 (inducible nitric oxide synthase, INOS) are inhibited by Glycyrrhizin acid. This product may act to suppress the growth and acid producing effects of S. mutans in vitro.
Glycyrrhizin Acid Ammonium Salt (CAS 53956-04-0) References
- Glycyrrhizic acid suppresses type 2 11 beta-hydroxysteroid dehydrogenase expression in vivo. | Tanahashi, T., et al. 2002. J Steroid Biochem Mol Biol. 80: 441-7. PMID: 11983491
- Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. | Cinatl, J., et al. 2003. Lancet. 361: 2045-6. PMID: 12814717
- Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP. | Thirugnanam, S., et al. 2008. Oncol Rep. 20: 1387-92. PMID: 19020719
- Efficacy and safety of addition of minor bloodletting (petit phlebotomy) in hepatitis C virus-infected patients receiving regular glycyrrhizin injections. | Tanaka, N., et al. 2009. J Gastroenterol. 44: 577-82. PMID: 19352587
- Effect of glycyrrhizin on pseudomonal skin infections in human-mouse chimeras. | Yoshida, S., et al. 2014. PLoS One. 9: e83747. PMID: 24497916
- Identification of differentially expressed miRNAs on normal cell, fatty liver cell and processed cell by monoammonium glycyrrhizinate from cattle (Bos indicus) by deep sequencing approach. | Huang, Y., et al. 2021. Anim Biotechnol. 32: 688-698. PMID: 32213006
- Combination of monoammonium glycyrrhizinate and cysteine hydrochloride ameliorated lipopolysaccharide/galactosamine-induced acute liver injury through Nrf2/ARE pathway. | Chu, S., et al. 2020. Eur J Pharmacol. 882: 173258. PMID: 32544505
- Micelle Formation of Monoammonium Glycyrrhizinate. | Matsuoka, K., et al. 2021. J Oleo Sci. 70: 911-918. PMID: 34193668
- Up-regulation of Nrf2/P62/Keap1 involves in the anti-fibrotic effect of combination of monoammonium glycyrrhizinate and cysteine hydrochloride induced by CCl4. | Chu, S., et al. 2021. Eur J Pharmacol. 913: 174628. PMID: 34774851
- Effect of Monoammonium Glycyrrhizinate on the Development of Hepatotoxicity After Initial Intrathecal Chemotherapy for Leukemia. | Kishimoto, K., et al. 2021. Anticancer Res. 41: 6231-6236. PMID: 34848478
- A Retrospective Study of Intrathecal Pemetrexed Combined With Systemic Therapy for Leptomeningeal Metastasis of Lung Cancer. | Geng, D., et al. 2022. Technol Cancer Res Treat. 21: 15330338221078429. PMID: 35289201
- Combination of monoammonium glycyrrhizinate and cysteine hydrochloride protects mice against acetaminophen-induced liver injury via Keap1/Nrf2/ARE pathway. | Li, J., et al. 2022. J Pharm Pharmacol. 74: 730-739. PMID: 35355074
- Protective effects of monoammonium glycyrrhizinate on fatty deposit degeneration induced in primary calf hepatocytes by sodium oleate administration in vitro. | Zhang, C., et al. 2022. Res Vet Sci. 150: 213-223. PMID: 35868152
- Monoammonium glycyrrhizinate improves antioxidant capacity of calf intestinal epithelial cells exposed to heat stress in vitro. | Wang, YX., et al. 2023. J Anim Sci.. PMID: 37155664
- Nitric oxide production in mouse peritoneal macrophages enhanced with glycyrrhizin. | Kondo, Y. and Takano, F. 1994. Biol Pharm Bull. 17: 759-61. PMID: 7920451
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glycyrrhizin Acid Ammonium Salt, 25 g | sc-203059 | 25 g | $67.00 |