Date published: 2026-4-2

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Glycocholic Acid, Sodium Salt (CAS 863-57-0)

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Alternate Names:
Sodium glycocholate
Application:
Glycocholic Acid, Sodium Salt is a biochemical formed by the conjugation of cholic acid with glycine
CAS Number:
863-57-0
Molecular Weight:
487.60
Molecular Formula:
C26H42NO6•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glycocholic acid, sodium salt (also known as sodium glycocholate) is a chemical compound with potential research applications. It is a conjugate of cholic acid, a bile acid, and glycine, an amino acid. The sodium salt form of glycocholic acid enhances its solubility in aqueous solutions. Researchers utilize glycocholic acid, sodium salt in various areas of study. It is used as a surfactant and emulsifying agent to improve the solubility, stability, and bioavailability of poorly soluble compounds. By incorporating glycocholic acid, sodium salt into formulations, researchers can enhance the absorption and efficacy of compounds, especially those with low water solubility.


Glycocholic Acid, Sodium Salt (CAS 863-57-0) References

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  2. The effect of bile salts on human vascular endothelial cells.  |  Garner, CM., et al. 1991. Biochim Biophys Acta. 1091: 41-5. PMID: 1995066
  3. Bile acids at neutral and acidic pH induce apoptosis and gene cleavages in nasopharyngeal epithelial cells: implications in chromosome rearrangement.  |  Tan, SN. and Sim, SP. 2018. BMC Cancer. 18: 409. PMID: 29649994
  4. Potential tumor-promoting activity of bile acids in rat glandular stomach.  |  Furihata, C., et al. 1987. Jpn J Cancer Res. 78: 32-9. PMID: 3102436
  5. Why is glycocholic acid sodium salt better than deoxycholic acid sodium salt for the preparation of mixed micelle injections?  |  Wang, T., et al. 2019. Food Sci Nutr. 7: 3675-3680. PMID: 31763016
  6. The effect of bile acids on the growth and global gene expression profiles in Akkermansia muciniphila.  |  Hagi, T., et al. 2020. Appl Microbiol Biotechnol. 104: 10641-10653. PMID: 33159542
  7. Characterization of a Human Sapovirus Genotype GII.3 Strain Generated by a Reverse Genetics System: VP2 Is a Minor Structural Protein of the Virion.  |  Li, TC., et al. 2022. Viruses. 14: PMID: 36016271
  8. Analysis of the effect of phototherapy on intestinal probiotics and metabolism in newborns with jaundice.  |  Fan, S., et al. 2022. Front Pediatr. 10: 878473. PMID: 36275061
  9. SLC46A3 is a lysosomal proton-coupled steroid conjugate and bile acid transporter involved in transport of active catabolites of T-DM1.  |  Tomabechi, R., et al. 2022. PNAS Nexus. 1: pgac063. PMID: 36741448
  10. Extraction of Pithecellobium clypearia Benth polysaccharides by dual-frequency ultrasound-assisted extraction: Structural characterization, antioxidant, hypoglycemic and anti-hyperlipidemic activities.  |  Chen, Z., et al. 2024. Ultrason Sonochem. 107: 106918. PMID: 38772313

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glycocholic Acid, Sodium Salt, 1 g

sc-280754
1 g
$92.00

Glycocholic Acid, Sodium Salt, 5 g

sc-280754A
5 g
$306.00