Date published: 2026-5-8

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Glycochenodeoxycholic acid (CAS 640-79-9)

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Alternate Names:
GCDCA NSC 681056
CAS Number:
640-79-9
Molecular Weight:
449.60
Molecular Formula:
C26H43NO5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Glycochenodeoxycholic acid (CAS 640-79-9) References

  1. Glycochenodeoxycholic acid inhibits calcium phosphate precipitation in vitro by preventing the transformation of amorphous calcium phosphate to calcium hydroxyapatite.  |  Qiu, SM., et al. 1991. J Clin Invest. 88: 1265-71. PMID: 1655828
  2. Glycochenodeoxycholic acid promotes proliferation of intestinal epithelia via reduction of cyclic AMP and increase in H2AX phosphorylation after exposure to γ-rays.  |  Ishizuka, S., et al. 2012. Biomed Res. 33: 159-65. PMID: 22790215
  3. Glycochenodeoxycholic acid impairs transcription factor E3 -dependent autophagy-lysosome machinery by disrupting reactive oxygen species homeostasis in L02 cells.  |  Lan, W., et al. 2020. Toxicol Lett. 331: 11-21. PMID: 32439580
  4. Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells.  |  Shi, C., et al. 2020. Aging (Albany NY). 12: 15546-15555. PMID: 32756004
  5. Plasma Bile Acid Profile in Patients with and without Type 2 Diabetes.  |  Mantovani, A., et al. 2021. Metabolites. 11: PMID: 34357347
  6. Bile acid metabolism and liver fibrosis following treatment with bifid triple viable capsules in nonalcoholic fatty liver disease.  |  Zhou, Y., et al. 2021. Am J Transl Res. 13: 13485-13497. PMID: 35035690
  7. Periductal bile acid exposure causes cholangiocyte injury and fibrosis.  |  Dotan, M., et al. 2022. PLoS One. 17: e0265418. PMID: 35294492
  8. Bile acid distributions, sex-specificity, and prognosis in colorectal cancer.  |  Cai, Y., et al. 2022. Biol Sex Differ. 13: 61. PMID: 36274154
  9. Akkermansia muciniphila protects mice against an emerging tick-borne viral pathogen.  |  Xie, J., et al. 2023. Nat Microbiol. 8: 91-106. PMID: 36604506
  10. Bile acid metabolites in early pregnancy and risk of gestational diabetes mellitus: Results from a prospective cohort study.  |  Wu, Y., et al. 2023. Diabetes Obes Metab. 25: 2255-2267. PMID: 37161712

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glycochenodeoxycholic acid, 100 µg

sc-507546
100 µg
$102.00