Molecular structure of Glycochenodeoxycholic acid 3-sulfate disodium salt, CAS Number: 66874-09-7
Glycochenodeoxycholic acid 3-sulfate disodium salt (CAS 66874-09-7)
Alternate Names:
Glycochenodeoxycholic Acid 3α-Sulfate Disodium Salt
Application:
Glycochenodeoxycholic acid 3-sulfate disodium salt is a bile salt formed from chenodeoxycholate and glycine
CAS Number:
66874-09-7
Molecular Weight:
573.65
Molecular Formula:
C26H41NNa2O8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Glycochenodeoxycholic acid 3-sulfate disodium salt is a bile salt formed from glycine (sc-29096) and chenodeoxycholate that acts as a detergent to solubilize fats for biological absorption. It is a cholagogue and choleretic. This compound serves as useful in studying the complex roles of bile acids and their derivatives in biological systems. Its enhanced solubility can facilitate experiments in aqueous environments, making it useful for investigating bile acid metabolism, signaling pathways, and their interactions with cellular receptors.
Glycochenodeoxycholic acid 3-sulfate disodium salt (CAS 66874-09-7) References
- Detection of Δ4-3-oxo-steroid 5β-reductase deficiency by LC-ESI-MS/MS measurement of urinary bile acids. | Muto, A., et al. 2012. J Chromatogr B Analyt Technol Biomed Life Sci. 900: 24-31. PMID: 22695323
- Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis. | Ressom, HW., et al. 2012. Anal Chim Acta. 743: 90-100. PMID: 22882828
- Power of metabolomics in diagnosis and biomarker discovery of hepatocellular carcinoma. | Wang, X., et al. 2013. Hepatology. 57: 2072-7. PMID: 23150189
- Prioritization of putative metabolite identifications in LC-MS/MS experiments using a computational pipeline. | Zhou, B., et al. 2013. Proteomics. 13: 248-60. PMID: 23307777
- Profile of bile acids in fetal gallbladder and meconium using liquid chromatography-tandem mass spectrometry. | Naritaka, N., et al. 2015. Clin Chim Acta. 446: 76-81. PMID: 25887994
- Improved synthesis of glycine, taurine and sulfate conjugated bile acids as reference compounds and internal standards for ESI-MS/MS urinary profiling of inborn errors of bile acid synthesis. | Donazzolo, E., et al. 2017. Chem Phys Lipids. 204: 43-56. PMID: 28300538
- A multiplex HRMS assay for quantifying selected human plasma bile acids as candidate OATP biomarkers. | Rago, B., et al. 2018. Bioanalysis. 10: 645-657. PMID: 29749252
- Comprehensive metabolic profiling of Parkinson's disease by liquid chromatography-mass spectrometry. | Shao, Y., et al. 2021. Mol Neurodegener. 16: 4. PMID: 33485385
- Radioimmunoassay of chenodeoxycholic acid-3-sulfate in urine. | Matsuoka, M. and Okumura, M. 1988. J Lipid Res. 29: 523-6. PMID: 3392468
- Analysis of 3-sulfated and nonsulfated bile acids by one-step solvolysis and high performance liquid chromatography. | Hirano, Y., et al. 1987. J Lipid Res. 28: 1524-9. PMID: 3430075
- Untargeted plasma metabolomics for risk prediction of hepatocellular carcinoma: A prospective study in two Chinese cohorts. | Hang, D., et al. 2022. Int J Cancer. 151: 2144-2154. PMID: 35904854
- Chenodeoxycholic acid-3-sulfate. Metabolism and excretion in the rat and hamster and effects on hepatic transport systems. | Eng, C. and Javitt, NB. 1983. Biochem Pharmacol. 32: 3555-8. PMID: 6651875
- Separation of sulfated from non-sulfated serum bile acids without the use of Sephadex columns. | Lepage, G., et al. 1981. J Lipid Res. 22: 705-11. PMID: 7276745
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glycochenodeoxycholic acid 3-sulfate disodium salt, 2.5 mg | sc-490322 | 2.5 mg | $398.00 |