Date published: 2026-4-24

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Glyco-SNAP-1 (CAS 188849-81-2)

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Application:
Glyco-SNAP-1 is a water-soluble nitric oxide donor
CAS Number:
188849-81-2
Purity:
≥96%
Molecular Weight:
381.40
Molecular Formula:
C13H23N3O8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glyco-SNAP-1 is a water-soluble nitric oxide (NO) donor. It is more stable than SNAP (sc-200319) in aqueous solution with or without EDTA, and is relatively stable at a high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as glutathione or cysteine.


Glyco-SNAP-1 (CAS 188849-81-2) References

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  2. Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide.  |  Bussolati, B., et al. 2001. Am J Pathol. 159: 993-1008. PMID: 11549592
  3. A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans.  |  Li, Z., et al. 2003. Blood. 101: 4423-9. PMID: 12576312
  4. GPIb-dependent platelet activation is dependent on Src kinases but not MAP kinase or cGMP-dependent kinase.  |  Marshall, SJ., et al. 2004. Blood. 103: 2601-9. PMID: 14684423
  5. Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells.  |  Wu, J., et al. 2005. J Lipid Res. 46: 1944-52. PMID: 15961787
  6. Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide-mediated angiogenesis.  |  Ahmad, S., et al. 2006. Circ Res. 99: 715-22. PMID: 16946136
  7. An inhaled inducible nitric oxide synthase inhibitor reduces damage of Candida-induced acute lung injury.  |  Ohsugi, S., et al. 2007. Biomed Res. 28: 91-9. PMID: 17510494
  8. FTY720P inhibits the Na+/K+ ATPase in Caco-2 cells via S1PR2: PGE2 and NO are along the signaling pathway.  |  Rida, R. and Kreydiyyeh, S. 2018. Life Sci. 215: 198-206. PMID: 30439376
  9. Regulation of nutrient and electrolyte absorption in human organoid-derived intestinal epithelial cell monolayers.  |  Haynes, J., et al. 2022. Transl Res. 248: 22-35. PMID: 35513245
  10. Signaling Cascade Mediating the Effect of FTY720P on the Na+/K+ ATPase in LLC-PK1.  |  Khalil, C., et al. 2022. Cell Physiol Biochem. 56: 418-435. PMID: 36041048
  11. IFN-gamma inhibits AP-1 binding activity in human brain-derived cells through a nitric oxide dependent mechanism.  |  Conant, K., et al. 1998. J Neuroimmunol. 88: 39-44. PMID: 9688322
  12. Specific S-nitrosothiol (thionitrite) quantification as solution nitrite after vanadium(III) reduction and ozone-chemiluminescent detection.  |  Ewing, JF. and Janero, DR. 1998. Free Radic Biol Med. 25: 621-8. PMID: 9741600
  13. Glyco-S-nitrosothiols: sugar-SNAP, a new type of nitric oxide donor.  |  Hou, Y., et al. 1999. Methods Enzymol. 301: 242-9. PMID: 9919573

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glyco-SNAP-1, 5 mg

sc-221680
5 mg
$270.00

Glyco-SNAP-1, 25 mg

sc-221680A
25 mg
$676.00