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Glycidyl propargyl ether (CAS 18180-30-8)

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Alternate Names:
2,3-Epoxypropyl propargyl ether
Application:
Glycidyl propargyl ether is a terminal alkyne epoxide compound for proteomics research
CAS Number:
18180-30-8
Purity:
≥90%
Molecular Weight:
112.13
Molecular Formula:
C6H8O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glycidyl propargyl ether is a terminal alkyne epoxide compound for proteomics research. Glycidyl propargyl ether (GPE) is an organic compound widely utilized in diverse applications, ranging from synthesis to scientific research and laboratory experiments. This colorless liquid possesses a low boiling point and emits a slightly sweet odor. Derived from propargyl alcohol, Glycidyl propargyl ether serves as a valuable component in various chemical reactions, including alkylation, condensation, and esterification. Moreover, it functions as a monomer in the manufacturing of polyurethanes and other polymers. In the realm of scientific research, Glycidyl propargyl ether finds application in investigating the structure and function of proteins, enzymes, and other molecules. It is instrumental in deciphering the mechanism of action of drugs and other compounds. With the assistance of a base catalyst, Glycidyl propargyl ether actively participates in alkylation, condensation, and esterification reactions. It also plays a significant role in the production of polyurethanes and other polymers.


Glycidyl propargyl ether (CAS 18180-30-8) References

  1. Propargyl-functional aliphatic polycarbonate obtained from carbon dioxide and glycidyl propargyl ether.  |  Hilf, J. and Frey, H. 2013. Macromol Rapid Commun. 34: 1395-400. PMID: 23893471
  2. High affinity phosphopeptides enrichment and desalting of biological materials on newly engineered poly(glycidyl propargyl ether/divinyl benzene).  |  Saeed, A., et al. 2013. Anal Chem. 85: 8979-86. PMID: 24006948
  3. A PEGylated alternating copolymer with oxidation-sensitive phenylboronic ester pendants for anticancer drug delivery.  |  Zhang, Y., et al. 2019. Biomater Sci. 7: 3898-3905. PMID: 31317137
  4. Dual signal amplification based on polysaccharide-initiated ring-opening polymerization and click polymerization for exosomes detection.  |  Zhu, X., et al. 2021. Talanta. 233: 122531. PMID: 34215034
  5. Effective Oxidation-Responsive Polyester Nanocarriers for Anti-Inflammatory Drug Delivery.  |  He, P., et al. 2021. Int J Nanomedicine. 16: 5053-5064. PMID: 34349508
  6. Polyglycidols with Two Orthogonal Protective Groups:  Preparation, Selective Deprotection, and Functionalization  |  Michael Erberich, Helmut Keul, and Martin Möller. 2007,. Macromolecules. 40, 9,: 3070–3079.
  7. One-step synthesis of multi-alkyne functional hyperbranched polyglycerols by copolymerization of glycidyl propargyl ether and glycidol†  |  Christoph Schüll,ab Tile Gieshoffa and Holger Frey*a. 2013,. Polym. Chem.,. 4,: 4730-4736.
  8. "Clickable PEG" via anionic copolymerization of ethylene oxide and glycidyl propargyl ether†  |  Jana Herzberger, ORCID logo ab Daniel Leibig,ab Jens Langhanki,a Christian Moers,ab Till Opatz ORCID logo a and Holger Frey*ab. 2017. Polym. Chem.,.,8,: 1882-1887.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glycidyl propargyl ether, 10 ml

sc-228260
10 ml
$185.00

Buenos días, soy María José de la Universidad de Castilla-La Mancha. Ciudad Real, España. Me gustaría saber si disponen de envases de glycidyl propargyl ether de mayor tamaño que 10 ml y su precio en ese caso. Muchas gracias de antemano.

Asked by: mjosecarrero
Buenos días María José, muchas gracias por su pregunta. Si nos envía un email a spain@scbt.com con la cantidad que necesita y si tienen algún requisito técnico (p.ej. Pureza mínima) estaremos encantados de considerar el pedido especial e informarle sobre todos los detalles lo antes posible. Good morning María José, thank you very much for your inquiry. If you send us an email to europe@scbt.com with the needed quantity and the required product specificities (e.g minimum purity) we will be happy to consider the Special Order and let you know all the details about it as soon as possible.
Answered by: Technical Support Europe
Date published: 2016-10-25
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Rated 5 out of 5 by from Various publications have cited the use ofVarious publications have cited the use of the terminal alkyne epoxide compound Glycidyl propargyl ether for proteomics research. -SCBT Publication Review
Date published: 2015-07-10
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Glycidyl propargyl ether is rated 5.0 out of 5 by 1.
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