Date published: 2025-9-25

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Glyceryl trioleate (CAS 122-32-7)

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Alternate Names:
1,2,3-Tri(cis-9-octadecenoyl)glycerol; (9Z)9-Octadecenoic acid 1,2,3-propanetriyl ester
CAS Number:
122-32-7
Molecular Weight:
885.43
Molecular Formula:
C57H104O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glyceryl trioleate, a triester of glycerol and oleic acid, is utilized in research for its role as a model lipid. In the study of lipid metabolism, it is an important compound for understanding the enzymatic processes of lipases, which are for the breakdown and synthesis of fatty acids and glycerol in living organisms. Material scientists investigate glyceryl trioleate for its lubricative properties, which can inform the development of bio-based lubricants. Additionally, glyceryl trioleate is utilized in the development of lipid-based chemical delivery systems due to its biocompatibility and ability to form stable structures like liposomes, which are key for encapsulating and transporting compounds. It also plays a role in bioenergy research, particularly in the optimization of biodiesel production, due to its relevance as a feedstock in transesterification reactions.


Glyceryl trioleate (CAS 122-32-7) References

  1. Genetic control of macrophage functions. I. Polygenic regulation of phagocytosis stimulation produced by Glyceryl Trioleate.  |  Mouton, D., et al. 1975. J Exp Med. 141: 306-21. PMID: 1113063
  2. A study of some factors influencing the stability of pharmaceutical emulsions. II. The effect of wax and specific gravity adjustment.  |  MULLINS, JD. and BECKER, CH. 1956. J Am Pharm Assoc Am Pharm Assoc. 45: 110-3. PMID: 13295117
  3. Regulation of postprandial blood metabolic variables by TEMPO-oxidized cellulose nanofibers.  |  Shimotoyodome, A., et al. 2011. Biomacromolecules. 12: 3812-8. PMID: 21902221
  4. Cationic solid lipid nanoparticles for co-delivery of paclitaxel and siRNA.  |  Yu, YH., et al. 2012. Eur J Pharm Biopharm. 80: 268-73. PMID: 22108492
  5. A simple strategy to monitor lipase activity using liquid crystal-based sensors.  |  Hu, QZ. and Jang, CH. 2012. Talanta. 99: 36-9. PMID: 22967518
  6. Thermo-oxidation of cholesterol: effect of the unsaturation degree of the lipid matrix.  |  Ansorena, D., et al. 2013. Food Chem. 141: 2757-64. PMID: 23871021
  7. Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy.  |  Wang, P., et al. 2013. Angew Chem Int Ed Engl. 52: 13042-6. PMID: 24127161
  8. Phase transfer of fatty acids into ultrasmall nanospheres for colorimetric detection of lipase and albumin.  |  Guo, C., et al. 2022. Chem Commun (Camb). 58: 5037-5040. PMID: 35377380
  9. Glyceryl trioleate-water partition coefficients for three simple organic compounds.  |  Platford, RF. 1979. Bull Environ Contam Toxicol. 21: 68-73. PMID: 444710
  10. The surface structure of mouse peritoneal cells--a study with the scanning electron microscope.  |  Carr, I., et al. 1969. J Microsc. 89: 105-11. PMID: 5819892
  11. Brain, liver, and adipose tissue erucic and very long chain fatty acid levels in adrenoleukodystrophy patients treated with glyceryl trierucate and trioleate oils (Lorenzo's oil).  |  Rasmussen, M., et al. 1994. Neurochem Res. 19: 1073-82. PMID: 7800117
  12. The pathophysiological changes of experimental fat embolism: early pre-hypoxaemic changes.  |  Sikorski, J., et al. 1977. Br J Surg. 64: 6-10. PMID: 831959
  13. Changes in articular cartilage following intraarticular injection of tritiated glyceryl trioleate.  |  Sprinz, R. and Stockwell, RA. 1976. J Anat. 122: 91-112. PMID: 977482

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glyceryl trioleate, 100 ml

sc-215092
100 ml
$48.00

Glyceryl trioleate, 1 L

sc-215092A
1 L
$130.00

Do you know the % fatty acid content of this chemical , thanks a lot

Asked by: George G
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2023-11-17

Hello, I would like to know the degree of purity of this product.

Asked by: Rafael Freire
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot.
Answered by: Tech Service
Date published: 2024-08-08
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Rated 5 out of 5 by from Worked great in our experimentsWorked great in our experiments.
Date published: 2015-10-19
Rated 5 out of 5 by from Kim HJ; et alKim HJ; et al. (PubMed ID: 26370800) utilized Glyceryl trioleate to test the activity of a lipolytic enzyme (lip7-3) from Bacillus sp. W130-35. -SCBT Publication Review
Date published: 2015-03-19
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Glyceryl trioleate is rated 5.0 out of 5 by 2.
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