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Glyceryl trioctanoate (CAS 538-23-8)

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Alternate Names:
1,2,3-Tricapryloylglycerol; Trioctanoin; Glycerol tricaprylate
Application:
Glyceryl trioctanoate is a triglyceride of octanoic acid esters
CAS Number:
538-23-8
Purity:
≥90%
Molecular Weight:
470.68
Molecular Formula:
C27H50O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glyceryl trioctanoate (tricaprylin) is a triglyceride of octanoic acid esters and a non-ionic surfactant. In vivo scientific research applications include the use of Glyceryl trioctanoate as a surfactant to improve drug delivery, an emulsifier in food products, and an emollient in cosmetics. In vitro applications use it as a substrate for various biochemical and physiological studies, a solvent for various chemical reactions, and a lubricant for laboratory equipment. It may act to increase the permeability of cell membranes, the solubility of lipids, and the activity of certain enzymes. Additionally, Glyceryl trioctanoate possesses anti-microbial activity.


Glyceryl trioctanoate (CAS 538-23-8) References

  1. Developmental changes in the pattern of ghrelin's acyl modification and the levels of acyl-modified ghrelins in murine stomach.  |  Nishi, Y., et al. 2005. Endocrinology. 146: 2709-15. PMID: 15746259
  2. A comparative study on two fungal lipases from Thermomyces lanuginosus and Yarrowia lipolytica shows the combined effects of detergents and pH on lipase adsorption and activity.  |  Aloulou, A., et al. 2007. Biochim Biophys Acta. 1771: 1446-56. PMID: 18022403
  3. Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein.  |  Janssen, S., et al. 2012. PLoS One. 7: e40168. PMID: 22768248
  4. Preparation and physicochemical properties of surfactant-free emulsions using electrolytic-reduction ion water containing lithium magnesium sodium silicate.  |  Okajima, M., et al. 2013. Drug Discov Ther. 7: 90-4. PMID: 23715508
  5. Limits of medium-chain and long-chain triacylglycerol utilization by neonatal piglets.  |  Chiang, SH., et al. 1990. J Anim Sci. 68: 1632-8. PMID: 2384363
  6. Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglycerides.  |  McDonald, TS., et al. 2014. J Cereb Blood Flow Metab. 34: 153-60. PMID: 24169853
  7. Short-chain flavor ester synthesis in organic media by an E. coli whole-cell biocatalyst expressing a newly characterized heterologous lipase.  |  Brault, G., et al. 2014. PLoS One. 9: e91872. PMID: 24670408
  8. A broad pH range indicator-based spectrophotometric assay for true lipases using tributyrin and tricaprylin.  |  Camacho-Ruiz, Mde L., et al. 2015. J Lipid Res. 56: 1057-67. PMID: 25748441
  9. Effects of a Tricaprylin Emulsion on Anti-glomerular Basement Membrane Glomerulonephritis in Rats: In Vivo and in Silico Studies.  |  Liu, N., et al. 2015. Biol Pharm Bull. 38: 1175-84. PMID: 26235580
  10. Unit cell structure of water-filled monoolein in inverted hexagonal mesophase in the presence of incorporated tricaprylin and entrapped lysozyme.  |  Kolev, V., et al. 2016. Eur Biophys J. 45: 99-112. PMID: 26424533
  11. Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function.  |  Tan, KN., et al. 2017. J Cereb Blood Flow Metab. 37: 2035-2048. PMID: 27418037
  12. Ultrasound pretreatment as a novel approach for intensification of lipase catalyzed esterification of tricaprylin.  |  More, SB., et al. 2017. Ultrason Sonochem. 36: 253-261. PMID: 28069208
  13. Self-Nanoemulsifying Drug Delivery Systems for Enhancing Solubility, Permeability, and Bioavailability of Sesamin.  |  Wang, CY., et al. 2020. Molecules. 25: PMID: 32650503
  14. Organization of the Interfacial Film of Nanoemulsions Stabilized by Porphyrin Derivatives.  |  Chapron, D., et al. 2023. Langmuir. 39: 1364-1372. PMID: 36680520
  15. Trioctanoin infusion increases in vivo leucine oxidation: a lesson in isotope modeling.  |  Rodriguez, N., et al. 1986. Am J Physiol. 251: E343-8. PMID: 3752242

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glyceryl trioctanoate, 100 ml

sc-215091
100 ml
$82.00

Glyceryl trioctanoate, 500 ml

sc-215091A
500 ml
$245.00

Glyceryl trioctanoate, 1 L

sc-215091B
1 L
$398.00