Date published: 2026-5-1

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Glycerol monostearate, purified (CAS 31566-31-1)

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Alternate Names:
Monostearin; Tegin; 1-mono-stearin
CAS Number:
31566-31-1
Molecular Weight:
358.56
Molecular Formula:
C21H42O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glycerol monostearate, purified is derived from the esterification of glycerol and stearic acid. This purified form of glycerol monostearate is a white, odorless powder that is soluble in water and other polar solvents. Scientifically, glycerol monostearate finds a wide range of applications in various industries. One of its primary uses is as an emulsifier and stabilizer in food and pharmaceutical products. It helps to prevent the separation of oil and water-based components in food products, such as ice cream, margarine, and baked goods. In pharmaceuticals, glycerol monostearate is utilized as a lubricant and binder in tablet formulations. Additionally, glycerol monostearate has significant scientific applications in the field of cosmetics and personal care. It is found in skincare products, such as creams, lotions, and moisturizers, due to its ability to enhance the texture and stability of emulsions. Glycerol monostearate acts as a humectant, attracting and retaining moisture on the skin, providing hydration and a smoother appearance. The mechanism of action of glycerol monostearate lies in its amphiphilic nature. As an emulsifier, it possesses both hydrophilic (water-loving) and lipophilic (fat-loving) properties. This allows it to interact with both water and oil molecules, forming stable emulsions. Glycerol monostearate forms a protective layer around oil droplets, preventing them from coalescing and maintaining a uniform dispersion within the system. Furthermore, in skincare products, glycerol monostearate functions by creating a barrier on the skin′s surface. This barrier helps to reduce water loss and retain moisture, promoting hydration and improving the skin′s overall texture. Additionally, it can contribute to the enhanced spreadability and absorption of cosmetic formulations, facilitating the delivery of active ingredients to the skin.


Glycerol monostearate, purified (CAS 31566-31-1) References

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  2. Design of lipid matrix particles for fenofibrate: effect of polymorphism of glycerol monostearate on drug incorporation and release.  |  Xia, D., et al. 2014. J Pharm Sci. 103: 697-705. PMID: 24375427
  3. Synergistic performance of lecithin and glycerol monostearate in oil/water emulsions.  |  Moran-Valero, MI., et al. 2017. Colloids Surf B Biointerfaces. 151: 68-75. PMID: 27987457
  4. Molecular dynamics simulation of effect of glycerol monostearate on amorphous polyethylene in the presence of water.  |  Iwata, S. 2017. J Mol Model. 23: 115. PMID: 28289957
  5. Physicochemical characterization of solid lipid nanoparticles comprised of glycerol monostearate and bile salts.  |  Talele, P., et al. 2018. Colloids Surf B Biointerfaces. 172: 517-525. PMID: 30212689
  6. Liraglutide attenuates renal tubular ectopic lipid deposition in rats with diabetic nephropathy by inhibiting lipid synthesis and promoting lipolysis.  |  Su, K., et al. 2020. Pharmacol Res. 156: 104778. PMID: 32247822
  7. Preparation and In Vivo Evaluation of a Lidocaine Self-Nanoemulsifying Ointment with Glycerol Monostearate for Local Delivery.  |  Kang, JH., et al. 2021. Pharmaceutics. 13: PMID: 34575544
  8. Correction: Kang et al. Preparation and In Vivo Evaluation of a Lidocaine Self-Nanoemulsifying Ointment with Glycerol Monostearate for Local Delivery. Pharmaceutics 2021, 13, 1468.  |  Kang, JH., et al. 2022. Pharmaceutics. 14: PMID: 35057114
  9. Correction: Preparation of glycerol monostearate from glycerol carbonate and stearic acid.  |  Han, L. and Wang, T. 2018. RSC Adv. 8: 21029. PMID: 35543986
  10. Effect and mechanism of glycerol monostearate dimer (GMS-D) and baking-treatment on the structure, in vitro digestion of gelatinized potato starch-GMS-D.  |  Lu, Y., et al. 2022. J Food Sci. 87: 3447-3458. PMID: 35810333
  11. Rheology and Tribology of Ethylcellulose-Based Oleogels and W/O Emulsions as Fat Substitutes: Role of Glycerol Monostearate.  |  Zhang, R., et al. 2022. Foods. 11: PMID: 35954132
  12. Effect of Potato Starch Hydrogel:Glycerol Monostearate Oleogel Ratio on the Physico-Rheological Properties of Bigels.  |  Alves Barroso, L., et al. 2022. Gels. 8: PMID: 36354602
  13. Demulsification of water-in-oil emulsions stabilized with glycerol monostearate crystals.  |  El-Aooiti, M., et al. 2023. J Colloid Interface Sci. 636: 637-645. PMID: 36680954

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glycerol monostearate, purified, 250 g

sc-269216
250 g
$61.00

Glycerol monostearate, purified, 1 kg

sc-269216A
1 kg
$158.00

Glycerol monostearate, purified, 5 kg

sc-269216B
5 kg
$474.00