Glycerol (CAS 56-81-5)
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Glycero is a simple polyol compound extensively utilized across various research domains due to its unique chemical properties. This trihydroxy alcohol is structurally comprised of a three-carbon backbone, each carbon atom bearing a hydroxyl group, making it highly soluble in water. The presence of these hydroxyl groups is pivotal for its role in numerous biochemical and physicochemical studies. In research, glycerol has been employed as a cryoprotectant in the cryopreservation of cells, tissues, and enzymes, where it aids in preventing the formation of ice crystals that can damage cellular structures. Its mechanism in this context is primarily through the reduction of the freezing point and the increase in the viscosity of the aqueous environment, which helps in stabilizing sensitive biomolecules during low-temperature storage. Additionally, glycerol is used as a component in gel electrophoresis buffers, serving to provide a denser medium which aids in the separation of nucleic acids and proteins by size. Moreover, due to its hygroscopic nature, glycerol is employed in scientific experiments that require the stabilization of moisture-sensitive reagents or environments, ensuring consistent experimental conditions. Its utility in research extends to being a standard for calibrating instruments that measure viscosity, demonstrating its broad applicability beyond biological systems.
Glycerol (CAS 56-81-5) References
- Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation. | Chi, EY., et al. 2003. Pharm Res. 20: 1325-36. PMID: 14567625
- Glycerol derivatives and sterols from Sargassum parvivesiculosum. | Qi, SH., et al. 2004. Chem Pharm Bull (Tokyo). 52: 986-8. PMID: 15304997
- Chemoselective catalytic conversion of glycerol as a biorenewable source to valuable commodity chemicals. | Zhou, CH., et al. 2008. Chem Soc Rev. 37: 527-49. PMID: 18224262
- Glycerol is a major substrate for glucose, glycogen, and nonessential amino acid synthesis in late-term chicken embryos. | Sunny, NE. and Bequette, BJ. 2011. J Anim Sci. 89: 3945-53. PMID: 21764833
- Content of plasmatic glycerol and activity of hepatic glycerol kinase in broiler chickens fed diets containing different sources and concentrations of glycerine. | Bernardino, VM., et al. 2014. J Anim Physiol Anim Nutr (Berl). 98: 328-37. PMID: 23692650
- Glycerol Solvates DPPC Headgroups and Localizes in the Interfacial Regions of Model Pulmonary Interfaces Altering Bilayer Structure. | Terakosolphan, W., et al. 2018. Langmuir. 34: 6941-6954. PMID: 29738253
- Enhancing methane yield from crude glycerol anaerobic digestion by coupling with ultrasound or A. niger/E. coli biodegradation. | Paulista, LO., et al. 2020. Environ Sci Pollut Res Int. 27: 1461-1474. PMID: 31749007
- A Direct Probe of the Hydrogen Bond Network in Aqueous Glycerol Aerosols. | Weeraratna, C., et al. 2021. J Phys Chem Lett. 12: 5503-5511. PMID: 34087076
- Bacillus atrophaeus NX-12 Utilizes Exosmotic Glycerol from Fusarium oxysporum f. sp. cucumerinum for Fengycin Production. | Xue, J., et al. 2023. J Agric Food Chem. 71: 10565-10574. PMID: 37410693
- The distribution and metabolism of glycerol in the rabbit. | Wade, AJ. 1981. Biochem J. 196: 547-56. PMID: 7316993
- Measuring glycerol turnover, gluconeogenesis from glycerol, and total gluconeogenesis with [2-13C] glycerol: role of the infusion-sampling mode. | Peroni, O., et al. 1996. Metabolism. 45: 897-901. PMID: 8692028
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glycerol, 100 ml | sc-29095A | 100 ml | $55.00 | |||
Glycerol, 1 L | sc-29095 | 1 L | $150.00 |