Molecular structure of Glutathione Monoethyl Ester, CAS Number: 118421-50-4
Glutathione Monoethyl Ester (CAS 118421-50-4)
See product citations (17)
Alternate Names:
Glutathione Monoethyl Ester also known as γ-GCE; L-γ-Glutamyl-L-cysteinyl Ethyl Glycinate; GSH-MEE; Glutathione reduced ethyl ester
Application:
Glutathione Monoethyl Ester is a membrane permeable derivative of GSH that can supplement cellular GSH levels
CAS Number:
118421-50-4
Purity:
>90%
Molecular Weight:
335.38
Molecular Formula:
C12H21N3O6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Glutathione Monoethyl Ester is a cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of Glutathione Monoethyl Ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals. Glutathione Monoethyl Ester is a protective agent against cellular damage such as in cataracts and mitochondrial degeneration.
Glutathione Monoethyl Ester (CAS 118421-50-4) References
- Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice. | Chen, TS., et al. 2000. Mech Ageing Dev. 120: 127-39. PMID: 11087910
- Glutathione monoethyl ester ameliorates caerulein-induced pancreatitis in the mouse. | Neuschwander-Tetri, BA., et al. 1992. J Clin Invest. 89: 109-16. PMID: 1370292
- Glutathione monoethyl ester provides neuroprotection in a rat model of stroke. | Anderson, MF., et al. 2004. Neurosci Lett. 354: 163-5. PMID: 14698463
- Glutathione ester protects against hydroxynonenal-induced loss of auditory hair cells. | Ruiz, JW., et al. 2006. Otolaryngol Head Neck Surg. 135: 792-7. PMID: 17071314
- Glutathione monoesters. | Anderson, ME. and Meister, A. 1989. Anal Biochem. 183: 16-20. PMID: 2619041
- Stimulation of cell proliferation by glutathione monoethyl ester in aged bone marrow stromal cells is associated with the assistance of TERT gene expression and telomerase activity. | Aminizadeh, N., et al. 2016. In Vitro Cell Dev Biol Anim. 52: 772-81. PMID: 27251157
- Glutathione monoethyl ester prevents TDP-43 pathology in motor neuronal NSC-34 cells. | Chen, T., et al. 2018. Neurochem Int. 112: 278-287. PMID: 28818672
- Preincubation with glutathione ethyl ester improves the developmental competence of vitrified mouse oocytes. | Li, Z., et al. 2018. J Assist Reprod Genet. 35: 1169-1178. PMID: 29876682
- Ultrasmall Gold Nanoparticles Coated with Zwitterionic Glutathione Monoethyl Ester: A Model Platform for the Incorporation of Functional Peptides. | Knittel, LL., et al. 2020. J Phys Chem B. 124: 3892-3902. PMID: 32352799
- Glutathione Ethyl Ester Protects In Vitro-Maturing Bovine Oocytes against Oxidative Stress Induced by Subsequent Vitrification/Warming. | García-Martínez, T., et al. 2020. Int J Mol Sci. 21: PMID: 33066129
- Comparison of the delivery of reduced glutathione into P388D1 cells by reduced glutathione and its mono- and diethyl ester derivatives. | Minhas, HS. and Thornalley, PJ. 1995. Biochem Pharmacol. 49: 1475-82. PMID: 7763291
- Protective effect of glutathione (GSH) over glutathione monoethyl-ester (GSH-E) on cold preservation of isolated rat liver cells. | Rodríguez, JV., et al. 1995. Cell Transplant. 4: 245-51. PMID: 7773558
- Disposition of glutathione monoethyl ester in the rat: glutathione ester is a slow release form of extracellular glutathione. | Grattagliano, I., et al. 1995. J Pharmacol Exp Ther. 272: 484-8. PMID: 7853160
- Effect of glutathione monoethyl ester on glutathione level and cardiac energetics in reperfused pig heart. | Guarnieri, C., et al. 1993. Res Commun Chem Pathol Pharmacol. 81: 33-44. PMID: 8210688
- Transport of glutathione diethyl ester into human cells. | Levy, EJ., et al. 1993. Proc Natl Acad Sci U S A. 90: 9171-5. PMID: 8415673
Inhibitor of:
TGase2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glutathione Monoethyl Ester, 50 mg | sc-203974 | 50 mg | $78.00 | |||
Glutathione Monoethyl Ester, 100 mg | sc-203974A | 100 mg | $143.00 | |||
Glutathione Monoethyl Ester, 500 mg | sc-203974B | 500 mg | $362.00 | |||
Glutathione Monoethyl Ester, 5 g | sc-203974C | 5 g | $2705.00 |