Glutathione-diethyl ester (reduced) (CAS 97451-40-6)

Glutathione-diethyl ester (reduced) is a derivative of the naturally occurring tripeptide glutathione, which is pivotal in cellular antioxidant defense mechanisms. This specific ester form enhances the bioavailability of glutathione when introduced into biological systems, allowing for more effective penetration into cells compared to the native form. The chemical serves as a critical tool in oxidative stress research by facilitating the increase of intracellular glutathione levels. This increment is essential for studying various oxidative processes and the cellular responses to reactive oxygen species (ROS). Researchers utilize this compound to investigate how enhanced glutathione levels can influence redox-sensitive signaling pathways, gene expression, and overall cellular health. Moreover, Glutathione-diethyl ester is employed in experimental settings to assess the impact of glutathione on cellular detoxification processes, including the neutralization of harmful byproducts of metabolism and xenobiotic detoxification. Its use is crucial in the fields of molecular biology and biochemistry, particularly in studies related to aging, neurodegeneration, and the cellular mechanisms underlying stress responses. By modulating glutathione levels, scientists can dissect the protective roles of this peptide in maintaining cellular homeostasis against environmental and metabolic stress.