Glutathione Antibody (D8): sc-52399

Glutathione Antibody (D8) is a mouse monoclonal IgG2a antibody that detects Glutathione protein of non-species reactive by western blotting (WB) and immunoprecipitation (IP). Anti-Glutathione antibody (D8) is available as the non-conjugated format. Glutathione, a tripeptide composed of glutamine, cysteine, and glycine, plays a crucial role in cellular defense against oxidative stress, acting as a potent antioxidant. Glutathione is primarily located in the cytosol of cells, where Glutathione helps to maintain the redox balance and protect cellular components from damage caused by reactive oxygen species. The localization of Glutathione is vital because Glutathione allows for immediate response to oxidative stress, ensuring that cells can quickly neutralize harmful free radicals. Additionally, Glutathione is involved in various metabolic processes, including the detoxification of harmful compounds and the regulation of cellular signaling pathways. Anti-Glutathione antibody (D8) specifically targets this important protein, making Glutathione antibody (D8) an invaluable tool for researchers studying oxidative stress, cellular metabolism, and related pathologies.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Glutathione Antibody (D8) References:

1. Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.  |  Duarte, AI., et al. 2005. Free Radic Biol Med. 39: 876-89. PMID: 16140208
2. Effects on skeletal muscle glutathione status of ischemia and reperfusion following abdominal aortic aneurysm surgery.  |  Westman, B., et al. 2006. Ann Vasc Surg. 20: 99-105. PMID: 16378152
3. Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum.  |  Burdo, J., et al. 2006. J Histochem Cytochem. 54: 549-57. PMID: 16399997
4. Excretory-secretory product of fasciola hepatica worm protects against Schistosoma mansoni infection in mice.  |  Hamed, MA. 2006. Indian J Exp Biol. 44: 554-61. PMID: 16872044
5. The role of thiols in liver ischemia-reperfusion injury.  |  Glantzounis, GK., et al. 2006. Curr Pharm Des. 12: 2891-901. PMID: 16918419
6. Glutamine in critical care: current evidence from systematic reviews.  |  Avenell, A. 2006. Proc Nutr Soc. 65: 236-41. PMID: 16923308
7. Taurine ameliorates water avoidance stress-induced degenerations of gastrointestinal tract and liver.  |  Zeybek, A., et al. 2006. Dig Dis Sci. 51: 1853-61. PMID: 16944297
8. Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy.  |  Meister, A. 1991. Pharmacol Ther. 51: 155-94. PMID: 1784629
9. Glutathione: subcellular distribution and membrane transport 1.  |  Oestreicher, J. and Morgan, B. 2019. Biochem Cell Biol. 97: 270-289. PMID: 30427707
10. The antioxidant glutathione.  |  Averill-Bates, DA. 2023. Vitam Horm. 121: 109-141. PMID: 36707132
11. Purification and properties of an abnormal glutathione reductase from human erythrocytes.  |  Staal, GE., et al. 1969. Biochim Biophys Acta. 185: 63-9. PMID: 5796112
12. The growth of neurites from explants of brachial spinal cord exposed to different components of wing bud mesenchyme.  |  Nurcombe, V. and Bennett, MR. 1983. J Comp Neurol. 219: 133-42. PMID: 6619337

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Glutathione Antibody (D8) has 17 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Glutathione Antibody (D8) Specifications

Alternate Product Name: Glutathione

Product Clone Name: D8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Glutathione

Epitope Species: N/A

Product Reactivity/Detection: Glutathione-protein complexes

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 17 citations in various scientific publications

Available Conjugates/Forms for Glutathione Antibody (D8): N/A